Research Output

2012

Drug discovery 2012 and beyond

Rotella, D. P., 8 Mar 2012, In : ACS Medicinal Chemistry Letters. 3, 3, p. 172-173 2 p.

Research output: Contribution to journalComment/debate

5 Scopus citations

Electron correlation methods based on the random phase approximation

Eshuis, H., Bates, J. E. & Furche, F., 1 Jan 2012, In : Theoretical Chemistry Accounts. 131, 1, 1084.

Research output: Contribution to journalArticle

256 Scopus citations

Erratum: Inhibition of soluble guanylate cyclase by ODQ (Biochemistry (2000) 39:35 (10848-10854) DOI:10.1021/bi9929296)

Zhao, Y., Brandish, P. E., Di Valentin, M., Schelvis, J. P. M., Babcock, G. T. & Marletta, M. A., 27 Nov 2012, In : Biochemistry. 51, 47, 1 p.

Research output: Contribution to journalComment/debate

Gold(i)-catalysed synthesis of cyclic sulfamidates by intramolecular allene hydroamination

Higginbotham, M. C. M. & Bebbington, M. W. P., 7 Aug 2012, In : Chemical Communications. 48, 61, p. 7565-7567 3 p.

Research output: Contribution to journalArticle

22 Scopus citations

HPLC/APCI mass spectrometry of saturated and unsaturated hydrocarbons by using hydrocarbon solvents as the APCI reagent and HPLC mobile phase

Gao, J., Owen, B. C., Borton, D. J., Jin, Z. & Kenttämaa, H. I., 1 May 2012, In : Journal of the American Society for Mass Spectrometry. 23, 5, p. 816-822 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Ion-molecule reactions for the differentiation of primary, secondary and tertiary hydroxyl functionalities in protonated analytes in a tandem mass spectrometer

Fu, M., Duan, P., Gao, J. & Kenttämaa, H. I., 21 Dec 2012, In : Analyst. 137, 24, p. 5720-5722 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

Pioneer and Analogue Drugs

Fischer, J., Ganellin, C. R. & Rotella, D. P., 18 Dec 2012, Analogue-Based Drug Discovery III. Wiley-VCH, p. 1-19 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Platinum nanoparticles anchored on chelating group-modified graphene for methanol oxidation

Wietecha, M. S., Zhu, J., Gao, G., Wang, N., Feng, H., Gorring, M. L., Kasner, M. & Hou, S., 15 Jan 2012, In : Journal of Power Sources. 198, p. 30-35 6 p.

Research output: Contribution to journalArticle

52 Scopus citations

Preface

Fischer, J., Ganellin, C. R. & Rotella, D. P., 18 Dec 2012, Analogue-Based Drug Discovery III. Wiley-VCH, p. xiii-xiv

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

Recent results in protein kinase inhibition for tropical diseases

Rotella, D. P., 15 Nov 2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 22, p. 6788-6793 6 p.

Research output: Contribution to journalReview article

15 Scopus citations

Stability and lifetime of potassium solid-contact ion selective electrodes for continuous and autonomous measurements

McElhoney, K., O'Neil, G. D., Chaniotakis, N. A. & Kounaves, S. P., 1 Nov 2012, In : Electroanalysis. 24, 11, p. 2071-2078 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Substituent effects on the nonradical reactivity of 4-dehydropyridinium cation

Jankiewicz, B. J., Gao, J., Reece, J. N., Vinueza, N. R., Narra, P., Nash, J. J. & Kenttämaa, H. I., 29 Mar 2012, In : Journal of Physical Chemistry A. 116, 12, p. 3089-3093 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Synthesis of (L)-4-fluorotryptophan

Konas, D. W., Seci, D. & Tamimi, S., 1 Jan 2012, In : Synthetic Communications. 42, 1, p. 144-152 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Welcome to pharmaceutical patent analyst

Jones, L. H., Rotella, D. P. & Doca, G., 1 Jan 2012, In : Pharmaceutical Patent Analyst. 1, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations
2011

An exploratory investigation of the risk of pathogenic contamination at selected New Jersey skilled nursing and assisted living residences

Feldman, C., Nothstein, G., Somaiya, C. K., Obeidallah, H., Silverthorne, E., Wunderlich, S. & Goodey, N. M., 1 Mar 2011, In : Perspectives in Public Health. 131, 2, p. 85-88 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

A parameter-free density functional that works for noncovalent interactions

Eshuis, H. & Furche, F., 5 May 2011, In : Journal of Physical Chemistry Letters. 2, 9, p. 983-989 7 p.

Research output: Contribution to journalArticle

109 Scopus citations

Carbon disulfide reagent allows the characterization of nonpolar analytes by atmospheric pressure chemical ionization mass spectrometry

Owen, B. C., Gao, J., Borton, D. J., Amundson, L. M., Archibold, E. F., Tan, X., Azyat, K., Tykwinski, R., Gray, M. & Kenttämaa, H. I., 30 Jul 2011, In : Rapid Communications in Mass Spectrometry. 25, 14, p. 1924-1928 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

Carbon-nanofiber-based nanocomposite membrane as a highly stable solid-state junction for reference electrodes

O'Neil, G. D., Buiculescu, R., Kounaves, S. P. & Chaniotakis, N. A., 15 Jul 2011, In : Analytical Chemistry. 83, 14, p. 5749-5753 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Catalytic contributions from remote regions of enzyme structure

Lee, J. & Goodey, N. M., 14 Dec 2011, In : Chemical Reviews. 111, 12, p. 7595-7624 30 p.

Research output: Contribution to journalReview article

42 Scopus citations

Determining nanocapillary geometry from electrochemical impedance spectroscopy using a variable topology network circuit model

Vitarelli, M. J., Prakash, S. & Talaga, D. S., 15 Jan 2011, In : Analytical Chemistry. 83, 2, p. 533-541 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Development of a fluorescently labeled thermostable DHFR for studying conformational changes associated with inhibitor binding

Goodey, N. M., Alapa, M. T., Hagmann, D. F., Korunow, S. G., Mauro, A. K., Kwon, K. S. & Hall, S. M., 30 Sep 2011, In : Biochemical and Biophysical Research Communications. 413, 3, p. 442-447 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Evidence for concerted electron proton transfer in charge recombination between FADH- and 306Trp in Escherichia coli photolyase

Zieba, A. A., Richardson, C., Lucero, C., Dieng, S. D., Gindt, Y. M. & Schelvis, J. P. M., 25 May 2011, In : Journal of the American Chemical Society. 133, 20, p. 7824-7836 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

Evidence from thermodynamics that DNA photolyase recognizes a solvent-exposed CPD lesion

Wilson, T. J., Crystal, M. A., Rohrbaugh, M. C., Sokolowsky, K. P. & Gindt, Y. M., 24 Nov 2011, In : Journal of Physical Chemistry B. 115, 46, p. 13746-13754 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Human p38 mitogen-activated protein kinase inhibitor drugs inhibit Plasmodium falciparum replication

Brumlik, M. J., Nkhoma, S., Kious, M. J., Thompson, G. R., Patterson, T. F., Siekierka, J. J., Anderson, T. J. C. & Curiel, T. J., 1 Jun 2011, In : Experimental Parasitology. 128, 2, p. 170-175 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Laboratory analysis of vitamin C in vegetables served in eldercare facilities and evaluation of related public nutrient database information

Konas, D. W., Feldman, C., Anand, B., Piemonte, J., Garay, C., Silverthorne, E. & Wunderlich, S. M., 1 Jan 2011, In : Topics in Clinical Nutrition. 26, 1, p. 68-77 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Laser-induced acoustic desorption/ atmospheric pressure chemical ionization mass spectrometry

Gao, J., Borton, D. J., Owen, B. C., Jin, Z., Hurt, M., Amundson, L. M., Madden, J. T., Qian, K. & Kenttämaa, H. I., 1 Mar 2011, In : Journal of the American Society for Mass Spectrometry. 22, 3, p. 531-538 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Prediction of residues involved in inhibitor specificity in the dihydrofolate reductase family

Goodey, N. M., Herbert, K. G., Hall, S. M. & Bagley, K. C., 1 Dec 2011, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1814, 12, p. 1870-1879 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

The role of a Brugia malayi p38 MAP kinase ortholog (Bm-MPK1) in parasite anti-oxidative stress responses

Patel, A., Chojnowski, A. N., Gaskill, K., De Martini, W., Goldberg, R. L. & Siekierka, J. J., 1 Apr 2011, In : Molecular and Biochemical Parasitology. 176, 2, p. 90-97 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

The synthesis and cyclic voltammetry of select ferrocene piano-stool isocyanide complexes

Humphrey, B. D., Castilo, R. E., Vega, A. H., Feliciano, A. & Squires, M. E., 15 Mar 2011, In : Inorganica Chimica Acta. 368, 1, p. 271-274 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
2010

A 1,1′-ferrocenyl phosphine-borane: Synthesis, structure and evaluation in Rh-catalyzed hydroformylation

Bebbington, M. W. P., Bontemps, S., Bouhadir, G., Hanton, M. J., Tooze, R. P., Van Rensburg, H. & Bourissou, D., 1 Aug 2010, In : New Journal of Chemistry. 34, 8, p. 1556-1559 4 p.

Research output: Contribution to journalArticle

39 Scopus citations
23 Scopus citations

Apicomplexa, trypanosoma and parasitic nematode protein kinases as antiparasitic therapeutic targets

Liotta, F. & Siekierka, J. J., 1 Feb 2010, In : Current Opinion in Investigational Drugs. 11, 2, p. 147-156 10 p.

Research output: Contribution to journalReview article

15 Scopus citations
146 Scopus citations

Formation of highly stable dispersions of silane-functionalized reduced graphene oxide

Hou, S., Su, S., Kasner, M. L., Shah, P., Patel, K. & Madarang, C. J., 6 Dec 2010, In : Chemical Physics Letters. 501, 1-3, p. 68-74 7 p.

Research output: Contribution to journalArticle

156 Scopus citations

Highly sensitive and selective dopamine biosensor fabricated with silanized graphene

Hou, S., Kasner, M. L., Su, S., Patel, K. & Cuellari, R., 9 Sep 2010, In : Journal of Physical Chemistry C. 114, 35, p. 14915-14921 7 p.

Research output: Contribution to journalArticle

202 Scopus citations

How penetrable are thioalkyl self-assembled monolayers?

Waring, C., Bagot, P. A. J., Bebbington, M. W. P., Räisänen, M. T., Buck, M., Costen, M. L. & McKendrick, K. G., 1 Jul 2010, In : Journal of Physical Chemistry Letters. 1, 13, p. 1917-1921 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

In vitro formation of amyloid from α-synuclein is dominated by reactions at hydrophobic interfaces

Pronchik, J., He, X., Giurleo, J. T. & Talaga, D. S., 21 Jul 2010, In : Journal of the American Chemical Society. 132, 28, p. 9797-9803 7 p.

Research output: Contribution to journalArticle

78 Scopus citations

Peroxisomal plant 3-ketoacyl-CoA thiolase structure and activity are regulated by a sensitive redox switch

Pye, V. E., Christensen, C. E., Dyer, J. H., Arent, S. & Henriksen, A., 30 Jul 2010, In : Journal of Biological Chemistry. 285, 31, p. 24078-24088 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Potent dihydroquinolinone dopamine D2 partial agonist/serotonin reuptake inhibitors for the treatment of schizophrenia

Yan, Y., Zhou, P., Rotella, D. P., Feenstra, R., Kruse, C. G., Reinders, J. H., Neut, M. V. D., Lai, M., Zhang, J., Kowal, D. M., Carrick, T., Marquis, K. L., Pausch, M. H. & Robichaud, A. J., 1 May 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 9, p. 2983-2986 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Resonance Raman characterization of the flavin radical in cryptochrome DASH

Schelvis, J. P. M., Lucero, C., Eisenberg, A. S. & Gindt, Y. M., 14 Dec 2010, XXII International Conference on Raman Spectroscopy, ICORS 2010. Vol. 1267. p. 284-285 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Role of Small Oligomers on the Amyloidogenic Aggregation Free-Energy Landscape

He, X., Giurleo, J. T. & Talaga, D. S., 8 Jan 2010, In : Journal of Molecular Biology. 395, 1, p. 134-154 21 p.

Research output: Contribution to journalArticle

20 Scopus citations

Selective Serotonin Reuptake Inhibitors for the Treatment of Depression

Childers, W. E. & Rotella, D. P., 30 Aug 2010, Analogue-Based Drug Discovery II. Wiley-VCH, p. 269-295 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Spectroscopic and thermodynamic comparisons of Escherichia coli DNA photolyase and Vibrio cholerae cryptochrome 1

Sokolowsky, K., Newton, M., Lucero, C., Wertheim, B., Freedman, J., Cortazar, F., Czochor, J., Schelvis, J. P. M. & Gindt, Y. M., 27 May 2010, In : Journal of Physical Chemistry B. 114, 20, p. 7121-7130 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

The distribution of DNA translocation times in solid-state nanopores

Li, J. & Talaga, D. S., 17 Nov 2010, In : Journal of Physics Condensed Matter. 22, 45, 454129.

Research output: Contribution to journalArticle

50 Scopus citations

WS-50030 [7-{4-[3-(1H-inden-3-yl)propyl]piperazin-1-yl}-1,3-benzoxazol- 2(3H)-one]: A novel dopamine D2 receptor partial agonist/serotonin reuptake inhibitor with preclinical antipsychotic-like and antidepressant-like activity

Brennan, J. A., Graf, R., Grauer, S. M., Navarra, R. L., Pulicicchio, C. M., Hughes, Z. A., Lin, Q., Wantuch, C., Rosenzweig-Lipson, S., Pruthi, F., Lai, M., Smith, D., Goutier, W., Van De Neut, M., Robichaud, A. J., Rotella, D., Feenstra, R. W., Kruse, C., Broqua, P., Beyer, C. E. & 3 others, McCreary, A. C., Pausch, M. H. & Marquis, K. L., 1 Jan 2010, In : Journal of Pharmacology and Experimental Therapeutics. 332, 1, p. 190-201 12 p.

Research output: Contribution to journalArticle

12 Scopus citations
2009

Alzheimer's disease: A light at the end of the tunnel?

Robichaud, A. J. & Rotella, D. P., 1 Mar 2009, In : Drug Development Research. 70, 2, p. 57-59 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations

American chemical society - 238th national meeting & exposition. Novel small molecule therapeutics

Rotella, D. P., 1 Oct 2009, In : IDrugs. 12, 10, p. 612-613 2 p.

Research output: Contribution to journalArticle

17 Scopus citations

Cloning, expression and purification of an acetoacetyl CoA thiolase from sunflower cotyledon

Dyer, J. H., Maina, A., Gomez, I. D., Cadet, M., Oeljeklaus, S. & Schiedel, A. C., 1 Jan 2009, In : International Journal of Biological Sciences. 5, 7, p. 736-744 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Dielectric response of tantalum oxide subject to induced ion bombardment during oblique sputter deposition

Barron, S. C., Noginov, M. M., Werder, D., Schneemeyer, L. F. & Van Dover, R. B., 16 Dec 2009, In : Journal of Applied Physics. 106, 10, 104110.

Research output: Contribution to journalArticle

5 Scopus citations