Research Output

2006

Expression and Automated Purification of Acetoacetyl CoA Thiolase from Sunflower Cotyledon

Dyer, J. H., Becker, J., Geraldo, V. & Giron, M., Apr 2006, In : Journal of Laboratory Automation. 11, 2, p. 85-87 3 p.

Research output: Contribution to journalArticle

Hidden Markov model analysis of multichromophore photobleaching

Messina, T. C., Kim, H., Giurleo, J. T. & Talaga, D. S., 24 Aug 2006, In : Journal of Physical Chemistry B. 110, 33, p. 16366-16376 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Information theoretical approach to single-molecule experimental design and interpretation

Talaga, D. S., 10 Aug 2006, In : Journal of Physical Chemistry A. 110, 31, p. 9743-9757 15 p.

Research output: Contribution to journalArticle

15 Scopus citations

Inhibitors of unactivated p38 MAP kinase

Bullington, J., Argentieri, D., Averill, K., Carter, D., Cavender, D., Fahmy, B., Fan, X., Hall, D., Heintzelman, G., Jackson, P., Leung, W. P., Li, X., Ling, P., Olini, G., Razler, T., Reuman, M., Rupert, K., Russell, R., Siekierka, J., Wadsworth, S. & 3 others, Wolff, R., Xiang, B. & Zhang, Y. M., 1 Dec 2006, In : Bioorganic and Medicinal Chemistry Letters. 16, 23, p. 6102-6106 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Insight into framework destruction in ultramarine pigments

Del Federico, E., Shöfberger, W., Schelvis, J., Kapetanaki, S., Tyne, L. & Jerschow, A., 6 Feb 2006, In : Inorganic Chemistry. 45, 3, p. 1270-1276 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

IPRO: An iterative computational protein library redesign and optimization procedure

Saraf, M. C., Moore, G. L., Goodey, N. M., Cao, V. Y., Benkovic, S. J. & Maranas, C. D., Jun 2006, In : Biophysical Journal. 90, 11, p. 4167-4180 14 p.

Research output: Contribution to journalArticle

41 Scopus citations

Phosphodiesterases

Rotella, D. P., 1 Nov 2006, Comprehensive Medicinal Chemistry II. Elsevier Ltd., Vol. 2. p. 919-957 39 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Resonance Raman spectra of the neutral and anionic radical semiquinones of flavin adenine dinucleotide in glucose oxidase revisited

Schelvis, J. P. M., Pun, D., Goyal, N. & Sokolova, O., 1 Aug 2006, In : Journal of Raman Spectroscopy. 37, 8, p. 822-829 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Role of Asp1393 in catalysis, flavin reduction, NADP(H) binding, FAD thermodynamics, and regulation of the nNOS flavoprotein

Konas, D. W., Takaya, N., Sharma, M. & Stuehr, D. J., 17 Oct 2006, In : Biochemistry. 45, 41, p. 12596-12609 14 p.

Research output: Contribution to journalArticle

20 Scopus citations

Studies on a total synthesis of the microbial immunosuppresive agent FR901483

Kropf, J. E., Meigh, I. C., Bebbington, M. W. P. & Weinreb, S. M., 5 Mar 2006, In : Journal of Organic Chemistry. 71, 5, p. 2046-2055 10 p.

Research output: Contribution to journalArticle

50 Scopus citations

The free energy of dissociation of oligomeric structure in phycocyanin is not linear with denaturant

Thoren, K. L., Connell, K. B., Robinson, T. E., Shellhamer, D. D., Tammaro, M. S. & Gindt, Y. M., 3 Oct 2006, In : Biochemistry. 45, 39, p. 12050-12059 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
53 Scopus citations
2005

A fluorescent "off-on-off" proton switch derived from natural products and further studies of first-generation fluorescent photoinduced electron transfer (PET) systems

De Silva, S. A., Loo, K. C., Amorelli, B., Pathirana, S. L., Nyakirang'ani, M., Dharmasena, M., Demarais, S., Dorcley, B., Pullay, P. & Salih, Y. A., 21 Jul 2005, In : Journal of Materials Chemistry. 15, 27-28, p. 2791-2795 5 p.

Research output: Contribution to journalReview article

38 Scopus citations

Altering protein specificity: Techniques and applications

Antikainen, N. M. & Martin, S. F., 15 Apr 2005, In : Bioorganic and Medicinal Chemistry. 13, 8, p. 2701-2716 16 p.

Research output: Contribution to journalReview article

49 Scopus citations

American Chemical Society - 229th National Meeting. Bench to pilot plant: 13-17 March 2005, San Diego, CA, USA

Rotella, D. P., 1 May 2005, In : IDrugs. 8, 5, p. 390-391 2 p.

Research output: Contribution to journalArticle

American Chemical Society - 229th National Meeting. Carbohydrate vaccines: 13-17 March 2005, San Diego, CA, USA

Rotella, D. P., 1 May 2005, In : IDrugs. 8, 5, p. 387-389 3 p.

Research output: Contribution to journalArticle

Conformation coupled enzyme catalysis: Single-molecule and transient kinetics investigation of dihydrofolate reductase

Antikainen, N. M., Smiley, R. D., Benkovic, S. J. & Hammes, G. G., 27 Dec 2005, In : Biochemistry. 44, 51, p. 16835-16843 9 p.

Research output: Contribution to journalArticle

91 Scopus citations

C-terminal tail residue Arg1400 enables NADPH to regulate electron transfer in neuronal nitric-oxide synthase

Tiso, M., Konas, D. W., Panda, K., Garcin, E. D., Sharma, M., Getzoff, E. D. & Stuehr, D. J., 25 Nov 2005, In : Journal of Biological Chemistry. 280, 47, p. 39208-39219 12 p.

Research output: Contribution to journalArticle

39 Scopus citations

Determination of residual triadimefon, triadimenol-a, triadimenol-b in corn by gel permeation chromatography and gas chromatography/mass spectrometry

Zhang, W., Gao, J., Chen, S. & Li, C., 1 Oct 2005, In : Fenxi Huaxue. 33, 10, p. 1442-1444 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Discovery and structure-activity relationships of 2-benzylpyrrolidine- substituted aryloxypropanols as calcium-sensing receptor antagonists

Yang, W., Wang, Y., Roberge, J. Y., Ma, Z., Liu, Y., Lawrence, R. M., Rotella, D. P., Seethala, R., Feyen, J. H. M. & Dickson, J. K., 15 Feb 2005, In : Bioorganic and Medicinal Chemistry Letters. 15, 4, p. 1225-1228 4 p.

Research output: Contribution to journalArticle

43 Scopus citations

Drug-eluting stents: Sirolimus and paclitaxel differentially affect cultured cells and injured arteries

Parry, T. J., Brosius, R., Thyagarajan, R., Carter, D., Argentieri, D., Falotico, R. & Siekierka, J., 7 Nov 2005, In : European Journal of Pharmacology. 524, 1-3, p. 19-29 11 p.

Research output: Contribution to journalArticle

99 Scopus citations

HIV-1 Nef-induced FasL induction and bystander killing requires p38 MAPK activation

Muthumani, K., Choo, A. Y., Hwang, D. S., Premkumar, A., Dayes, N. S., Harris, C., Green, D. R., Wadsworth, S. A., Siekierka, J. J. & Weiner, D. B., 15 Sep 2005, In : Blood. 106, 6, p. 2059-2068 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Mycobacterium tuberculosis KatG(S315T) catalase-peroxidase retains all active site properties for proper catalytic function

Kapetanaki, S. M., Chouchane, S., Yu, S., Zhao, X., Magliozzo, R. S. & Schelvis, J. P. M., 11 Jan 2005, In : Biochemistry. 44, 1, p. 243-252 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Proteins, peptides, amino acids and enzyme inhibitors. 28 August - 1 September 2005, Washington, DC, USA

Rotella, D. P., 1 Nov 2005, In : IDrugs. 8, 11, p. 878-879 2 p.

Research output: Contribution to journalArticle

Resonance Raman spectroscopy of Compound II and its decay in Mycobacterium tuberculosis catalase-peroxidase KatG and its isoniazid resistant mutant S315T

Kapetanaki, S. M., Chouchane, S., Yu, S., Magliozzo, R. S. & Schelvis, J. P. M., 1 Jun 2005, In : Journal of Inorganic Biochemistry. 99, 6, p. 1401-1406 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Solid-state NMR and resonance Raman studies of ultramarine pigments

Del Federico, E., Schoefberger, W., Kumar, R., Ling, W., Kapetanaki, S. M., Schelvis, J. & Jerschow, A., 19 Dec 2005, In : Materials Research Society Symposium Proceedings. 852, p. 247-254 8 p., OO5.4.

Research output: Contribution to journalConference article

3 Scopus citations

Substrate binding modulates the reduction potential of DNA photolyase

Gindt, Y. M., Schelvis, J. P. M., Thoren, K. L. & Huang, T. H., 3 Aug 2005, In : Journal of the American Chemical Society. 127, 30, p. 10472-10473 2 p.

Research output: Contribution to journalArticle

36 Scopus citations

Technical achievements in organic chemistry. 28 August - 1 September 2005, Washington, DC, USA

Rotella, D. P., 1 Nov 2005, In : IDrugs. 8, 11, p. 876-877 2 p.

Research output: Contribution to journalArticle

2004

A computational study of a fluorescent photoinduced electron transfer (PET) sensor for cations

De Silva, S. A., Kasner, M., Whitener, M. A. & Pathirana, S. L., 5 Dec 2004, In : International Journal of Quantum Chemistry. 100, 5, p. 753-757 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

A conserved aspartate (Asp-1393) regulates NADPH reduction of neuronal nitric-oxide synthase: Implications for catalysis

Panda, K., Adak, S., Konas, D., Sharma, M. & Stuehr, D. J., 30 Apr 2004, In : Journal of Biological Chemistry. 279, 18, p. 18323-18333 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

American Chemical Society - 228th National meeting. Technical achievements in organic synthesis

Rotella, D. P., 1 Oct 2004, In : IDrugs. 7, 10, p. 889-892 4 p.

Research output: Contribution to journalArticle

A modular laser apparatus for polarimetry nephelometry, and fluorimetry in general chemistry

Darveau, S. A., Mueller, J., Vaverka, A., Barta, C., Fitch, A., Jurzenski, J. & Gindt, Y., 1 Mar 2004, In : Journal of Chemical Education. 81, 3, p. 401-405 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

A novel role for the immunophilin FKBP52 in copper transport

Sanokawa-Akakura, R., Dai, H., Akakura, S., Weinstein, D., Fajardo, J. E., Lang, S. E., Wadsworth, S., Siekierka, J. & Birge, R. B., 2 Jul 2004, In : Journal of Biological Chemistry. 279, 27, p. 27845-27848 4 p.

Research output: Contribution to journalArticle

29 Scopus citations

A role for schwann cells in the neuroregenerative effects of a non-immunosuppressive FK506 derivative, JNJ460

Birge, R. B., Wadsworth, S., Akakura, R., Abeysinghe, H., Kanojia, R., Macielag, M., Desbarats, J., Escalante, M., Singh, K., Sundarababu, S., Parris, K., Childs, G., August, A., Siekierka, J. & Weinstein, D. E., 1 Jan 2004, In : Neuroscience. 124, 2, p. 351-366 16 p.

Research output: Contribution to journalArticle

34 Scopus citations

Cloning, expression, and purification of glyoxysomal 3-oxoacyl-CoA thiolase from sunflower cotyledons

Schiedel, A. C., Oeljeklaus, S., Minihan, P. & Dyer, J. H., Jan 2004, In : Protein Expression and Purification. 33, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Low-Cost Athermal Wavelength-Locker Integrated in a Temperature-Tuned Single-Frequency Laser Package

Ackerman, D. A., Paget, K. M., Schneemeyer, L. F., Ketelsen, L. J. P., Warning, F. W., Sjolund, O., Graebner, J. E., Kanan, A., Raju, V. R., Eng, L. E., Schaeffer, E. D. & Van Emmerik, P., 1 Jan 2004, In : Journal of Lightwave Technology. 22, 1, p. 166-171 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Novel "second-generation" approaches for the control of type 2 diabetes

Rotella, D. P., 12 Aug 2004, In : Journal of Medicinal Chemistry. 47, 17, p. 4111-4112 2 p.

Research output: Contribution to journalShort survey

50 Scopus citations

Phe393 Mutants of Cytochrome P450 BM3 with Modified Heme Redox Potentials Have Altered Heme Vinyl and Propionate Conformations

Chen, Z., Ost, T. W. B. & Schelvis, J. P. M., 24 Feb 2004, In : Biochemistry. 43, 7, p. 1798-1808 11 p.

Research output: Contribution to journalArticle

73 Scopus citations

Resonance Raman spectroscopy of the neutral radical Trp306 in DNA photolyase

Gurudas, U. & Schelvis, J. P. M., 13 Oct 2004, In : Journal of the American Chemical Society. 126, 40, p. 12788-12789 2 p.

Research output: Contribution to journalArticle

13 Scopus citations

SB-480848 (GlaxoSmithKline)

Rotella, D. P., 1 Mar 2004, In : Current Opinion in Investigational Drugs. 5, 3, p. 348-351 4 p.

Research output: Contribution to journalReview article

11 Scopus citations

Substrate electric dipole moment exerts a pH-dependent effect on electron transfer in Escherichia coli photolyase

Kapetanaki, S. M., Ramsey, M., Gindt, Y. M. & Schelvis, J. P. M., 26 May 2004, In : Journal of the American Chemical Society. 126, 20, p. 6214-6215 2 p.

Research output: Contribution to journalArticle

20 Scopus citations

Suppression of HIV-1 viral replication and cellular pathogenesis by a novel p38/JNK kinase inhibitor

Muthumani, K., Wadsworth, S. A., Dayes, N. S., Hwang, D. S., Choo, A. Y., Abeysinghe, H. R., Siekierka, J. J. & Weiner, D. B., 26 Mar 2004, In : AIDS. 18, 5, p. 739-748 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

The Codeposited Composition Spread Approach to High-Throughput Discovery/Exploration of Inorganic Materials

Van Dover, R. B. & Schneemeyer, L. F., 2 Jan 2004, In : Macromolecular Rapid Communications. 25, 1, p. 150-157 8 p.

Research output: Contribution to journalReview article

35 Scopus citations

The FAD-shielding residue Phe1395 regulates neuronal nitric-oxide synthase catalysis by controlling NADP+ affinity and a conformational equilibrium within the flavoprotein domain

Konas, D. W., Zhu, K., Sharma, M., Aulak, K. S., Brudvig, G. W. & Stuehr, D. J., 20 Aug 2004, In : Journal of Biological Chemistry. 279, 34, p. 35412-35425 14 p.

Research output: Contribution to journalArticle

45 Scopus citations

Wolfrom/Isbell New Investigator Award Symposium

Rotella, D. P., 1 Oct 2004, In : IDrugs. 7, 10, p. 893-894 2 p.

Research output: Contribution to journalArticle

2003

Altering substrate specificity of phosphatidylcholine-preferring phospholipase C of Bacillus cereus by random mutagenesis of the headgroup binding site

Antikainen, N. M., Hergenrother, P. J., Harris, M. M., Corbett, W. & Martin, S. F., 18 Feb 2003, In : Biochemistry. 42, 6, p. 1603-1610 8 p.

Research output: Contribution to journalArticle

31 Scopus citations