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2010

Highly sensitive and selective dopamine biosensor fabricated with silanized graphene

Hou, S., Kasner, M. L., Su, S., Patel, K. & Cuellari, R., 9 Sep 2010, In : Journal of Physical Chemistry C. 114, 35, p. 14915-14921 7 p.

Research output: Contribution to journalArticle

202 Scopus citations

How penetrable are thioalkyl self-assembled monolayers?

Waring, C., Bagot, P. A. J., Bebbington, M. W. P., Räisänen, M. T., Buck, M., Costen, M. L. & McKendrick, K. G., 1 Jul 2010, In : Journal of Physical Chemistry Letters. 1, 13, p. 1917-1921 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

In vitro formation of amyloid from α-synuclein is dominated by reactions at hydrophobic interfaces

Pronchik, J., He, X., Giurleo, J. T. & Talaga, D. S., 21 Jul 2010, In : Journal of the American Chemical Society. 132, 28, p. 9797-9803 7 p.

Research output: Contribution to journalArticle

78 Scopus citations

Peroxisomal plant 3-ketoacyl-CoA thiolase structure and activity are regulated by a sensitive redox switch

Pye, V. E., Christensen, C. E., Dyer, J. H., Arent, S. & Henriksen, A., 30 Jul 2010, In : Journal of Biological Chemistry. 285, 31, p. 24078-24088 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Potent dihydroquinolinone dopamine D2 partial agonist/serotonin reuptake inhibitors for the treatment of schizophrenia

Yan, Y., Zhou, P., Rotella, D. P., Feenstra, R., Kruse, C. G., Reinders, J. H., Neut, M. V. D., Lai, M., Zhang, J., Kowal, D. M., Carrick, T., Marquis, K. L., Pausch, M. H. & Robichaud, A. J., 1 May 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 9, p. 2983-2986 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Role of Small Oligomers on the Amyloidogenic Aggregation Free-Energy Landscape

He, X., Giurleo, J. T. & Talaga, D. S., 8 Jan 2010, In : Journal of Molecular Biology. 395, 1, p. 134-154 21 p.

Research output: Contribution to journalArticle

20 Scopus citations

Spectroscopic and thermodynamic comparisons of Escherichia coli DNA photolyase and Vibrio cholerae cryptochrome 1

Sokolowsky, K., Newton, M., Lucero, C., Wertheim, B., Freedman, J., Cortazar, F., Czochor, J., Schelvis, J. P. M. & Gindt, Y. M., 27 May 2010, In : Journal of Physical Chemistry B. 114, 20, p. 7121-7130 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

The distribution of DNA translocation times in solid-state nanopores

Li, J. & Talaga, D. S., 17 Nov 2010, In : Journal of Physics Condensed Matter. 22, 45, 454129.

Research output: Contribution to journalArticle

50 Scopus citations

WS-50030 [7-{4-[3-(1H-inden-3-yl)propyl]piperazin-1-yl}-1,3-benzoxazol- 2(3H)-one]: A novel dopamine D2 receptor partial agonist/serotonin reuptake inhibitor with preclinical antipsychotic-like and antidepressant-like activity

Brennan, J. A., Graf, R., Grauer, S. M., Navarra, R. L., Pulicicchio, C. M., Hughes, Z. A., Lin, Q., Wantuch, C., Rosenzweig-Lipson, S., Pruthi, F., Lai, M., Smith, D., Goutier, W., Van De Neut, M., Robichaud, A. J., Rotella, D., Feenstra, R. W., Kruse, C., Broqua, P., Beyer, C. E. & 3 others, McCreary, A. C., Pausch, M. H. & Marquis, K. L., 1 Jan 2010, In : Journal of Pharmacology and Experimental Therapeutics. 332, 1, p. 190-201 12 p.

Research output: Contribution to journalArticle

12 Scopus citations
2009

American chemical society - 238th national meeting & exposition. Novel small molecule therapeutics

Rotella, D. P., 1 Oct 2009, In : IDrugs. 12, 10, p. 612-613 2 p.

Research output: Contribution to journalArticle

17 Scopus citations

Cloning, expression and purification of an acetoacetyl CoA thiolase from sunflower cotyledon

Dyer, J. H., Maina, A., Gomez, I. D., Cadet, M., Oeljeklaus, S. & Schiedel, A. C., 1 Jan 2009, In : International Journal of Biological Sciences. 5, 7, p. 736-744 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Dielectric response of tantalum oxide subject to induced ion bombardment during oblique sputter deposition

Barron, S. C., Noginov, M. M., Werder, D., Schneemeyer, L. F. & Van Dover, R. B., 16 Dec 2009, In : Journal of Applied Physics. 106, 10, 104110.

Research output: Contribution to journalArticle

5 Scopus citations
9 Scopus citations

Role of the oxyferrous heme intermediate and distal side adduct radical in the catalase activity of Mycobacterium tuberculosis KatG revealed by the W107F mutant

Zhao, X., Yu, S., Ranguelova, K., Suarez, J., Metlitsky, L., Schelvis, J. P. M. & Magliozzo, R. S., 13 Mar 2009, In : Journal of Biological Chemistry. 284, 11, p. 7030-7037 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Single-molecule protein unfolding in solid state nanopores

Talaga, D. S. & Li, J., 8 Jul 2009, In : Journal of the American Chemical Society. 131, 26, p. 9287-9297 11 p.

Research output: Contribution to journalArticle

266 Scopus citations

Tetrahydrocarbazole-based serotonin reuptake inhibitor/dopamine D2 partial agonists for the potential treatment of schizophrenia

Rotella, D. P., McFarlane, G. R., Greenfield, A., Grosanu, C., Robichaud, A. J., Denny, R. A., Feenstra, R. W., Núñez-García, S., Reinders, J. H., Neut, M. V. D., McCreary, A., Kruse, C. G., Sullivan, K., Pruthi, F., Lai, M., Zhang, J., Kowal, D. M., Carrick, T., Grauer, S. M., Navarra, R. L. & 4 others, Graf, R., Brennan, J., Marquis, K. L. & Pausch, M. H., 1 Oct 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 19, p. 5552-5555 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

The influence of initial conditions on charge transfer dynamics

Eshuis, H. & Van Voorhis, T., 19 Nov 2009, In : Physical Chemistry Chemical Physics. 11, 44, p. 10293-10298 6 p.

Research output: Contribution to journalArticle

14 Scopus citations
2008

American Chemical Society - 235th national meeting: Part 3

Rotella, D., 1 Jun 2008, In : IDrugs. 11, 6, p. 394-396 3 p.

Research output: Contribution to journalArticle

American Chemical Society - 236th National Meeting & Exposition. Drug development for tuberculosis and cancer

Rotella, D. P., 1 Oct 2008, In : IDrugs. 11, 10, p. 699-701 3 p.

Research output: Contribution to journalArticle

American Chemical Society - 236th National Meeting & Exposition. New Frontiers in Drug Delivery

Rotella, D. P., 1 Oct 2008, In : IDrugs. 11, 10, p. 702-704 3 p.

Research output: Contribution to journalArticle

19 Scopus citations

Differences in a conformational equilibrium distinguish catalysis by the endothelial and neuronal nitric-oxide synthase flavoproteins

Ilagan, R. P., Tiso, M., Konas, D. W., Hemann, C., Durra, D., Hille, R. & Stuehr, D. J., 11 Jul 2008, In : Journal of Biological Chemistry. 283, 28, p. 19603-19615 13 p.

Research output: Contribution to journalArticle

45 Scopus citations

Dynamics of molecules in strong oscillating electric fields using time-dependent Hartree-Fock theory

Eshuis, H., Balint-Kurti, G. G. & Manby, F. R., 28 Mar 2008, In : Journal of Chemical Physics. 128, 11, 114113.

Research output: Contribution to journalArticle

26 Scopus citations

Effect of the cyclobutane cytidine dimer on the properties of Escherichia coli DNA photolyase

Murphy, A. K., Tammaro, M., Cortazar, F., Gindt, Y. M. & Schelvis, J. P. M., 27 Nov 2008, In : Journal of Physical Chemistry B. 112, 47, p. 15217-15226 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Fluoride ion chelation by a bidentate phosphonium/borane lewis acid

Hudnall, T. W., Kim, Y. M., Bebbington, M. W. P., Bourissou, D. & Gabbaï, F. P., 20 Aug 2008, In : Journal of the American Chemical Society. 130, 33, p. 10890-10891 2 p.

Research output: Contribution to journalArticle

178 Scopus citations
7 Scopus citations

Impact of distal side water and residue 315 on ligand binding to ferric Mycobacterium tuberculosis catalase - Peroxidase (KatG)

Ranguelova, K., Suarez, J., Metlitsky, L., Yu, S., Brejt, S. Z., Brejt, S. Z., Zhao, L., Schelvis, J. P. M. & Magliozzo, R. S., 25 Nov 2008, In : Biochemistry. 47, 47, p. 12583-12592 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Medicinal Chemistry - XXth International Symposium. Lead finding strategies and kinase selectivity

Rotella, D. P., 1 Nov 2008, In : IDrugs. 11, 11, p. 774-778 5 p.

Research output: Contribution to journalArticle

Medicinal Chemistry - XXth International Symposium. Natural products and neurodegenerative diseases

Rotella, D. P., 1 Nov 2008, In : IDrugs. 11, 11, p. 779-782 4 p.

Research output: Contribution to journalArticle

Separation and analysis of dynamic stokes shift with multiple fluorescence environments: Coumarin 153 in bovine β-lactoglobulin A

Pronchik, J., Giurleo, J. T. & Talaga, D. S., 11 Sep 2008, In : Journal of Physical Chemistry B. 112, 36, p. 11422-11434 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

β-Lactoglobulin Assembles into Amyloid through Sequential Aggregated Intermediates

Giurleo, J. T., He, X. & Talaga, D. S., 19 Sep 2008, In : Journal of Molecular Biology. 381, 5, p. 1332-1348 17 p.

Research output: Contribution to journalArticle

51 Scopus citations
2007

3,3′,5,5′-Tetramethylbiphenyl-4,4′-dicarbonitrile

Britton, D. & De Silva, S. A., 1 Dec 2007, In : Acta Crystallographica Section E: Structure Reports Online. 63, 5

Research output: Contribution to journalArticle

Ambiphilic compounds: Synthesis and structure of a phosphane-borane with a flexible diphenyl ether tether

Bebbington, M. W. P., Bouhadir, G. & Bourissou, D., 1 Oct 2007, In : European Journal of Organic Chemistry. 27, p. 4483-4486 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

American Chemical Society - 233rd national meeting. CNS, cancer and cardiovascular targets

Rotella, D., 1 May 2007, In : IDrugs. 10, 5, p. 310-312 3 p.

Research output: Contribution to journalArticle

American Chemical Society - 234th National meeting - Syntheses of novel compounds and data on novel therapeutics

Rotella, D., 1 Oct 2007, In : IDrugs. 10, 10, p. 681-685 5 p.

Research output: Contribution to journalArticle

Drugs designed to inhibit human p38 mitogen-activated protein kinase activation treat Toxoplasma gondii and Encephalitozoon cuniculi infection

Wei, S., Daniel, B. J., Brumlik, M. J., Burow, M. E., Zou, W., Khan, I. A., Wadsworth, S., Siekierka, J. & Curiel, T. J., 1 Dec 2007, In : Antimicrobial Agents and Chemotherapy. 51, 12, p. 4324-4328 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Efficient soluble polymer-supported tartrate/Ti catalyst for asymmetric oxidation of prochiral sulfides

Gao, J., Guo, H., Liu, S. & Wang, M., 26 Nov 2007, In : Tetrahedron Letters. 48, 48, p. 8453-8455 3 p.

Research output: Contribution to journalArticle

24 Scopus citations

Modification of the active site of Mycobacterium tuberculosis KatG after disruption of the Met-Tyr-Trp cross-linked adduct

Kapetanaki, S. M., Zhao, X., Yu, S., Magliozzo, R. S. & Schelvis, J. P. M., 1 Mar 2007, In : Journal of Inorganic Biochemistry. 101, 3, p. 422-433 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

New advances of asymmetric cyclopropanation reactions using chiral metal catalysts

Gao, J. S., Bian, Q. H., Guo, H. C. & Wang, M., 1 Apr 2007, In : Chinese Journal of Organic Chemistry. 27, 4, p. 438-448 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Photoisomerizable heterodienes derived from a phosphine borane

Bebbington, M. W. P., Bontemps, S., Bouhadir, G. & Bourissou, D., 2 Jul 2007, In : Angewandte Chemie - International Edition. 46, 18, p. 3333-3336 4 p.

Research output: Contribution to journalArticle

71 Scopus citations

Potent non-nitrile dipeptidic dipeptidyl peptidase IV inhibitors

Simpkins, L. M., Bolton, S., Pi, Z., Sutton, J. C., Kwon, C., Zhao, G., Magnin, D. R., Augeri, D. J., Gungor, T., Rotella, D. P., Sun, Z., Liu, Y., Slusarchyk, W. S., Marcinkeviciene, J., Robertson, J. G., Wang, A., Robl, J. A., Atwal, K. S., Zahler, R. L., Parker, R. A. & 2 others, Kirby, M. S. & Hamann, L. G., 1 Dec 2007, In : Bioorganic and Medicinal Chemistry Letters. 17, 23, p. 6476-6480 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Protein free energy landscapes remodeled by ligand binding

Messina, T. C. & Talaga, D. S., Jul 2007, In : Biophysical Journal. 93, 2, p. 579-585 7 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Redox titration of ferricyanide to ferrocyanide with ascorbic acid: Illustrating the Nernst equation and beer-Lambert law

Huang, T. H., Salter, G., Kahn, S. L. & Gindt, Y. M., 1 Sep 2007, In : Journal of Chemical Education. 84, 9, p. 1461-1463 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

Reductase domain of Drosophila melanogaster nitric-oxide synthase: Redox transformations, regulation, and similarity to mammalian homologues

Ray, S. S., Sengupta, R., Tiso, M., Haque, M. M., Sahoo, R., Konas, D. W., Aulak, K., Regulski, M., Tully, T., Stuehr, D. J. & Ghosh, S., 23 Oct 2007, In : Biochemistry. 46, 42, p. 11865-11873 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Resonance Raman spectroscopic investigation of the light-harvesting chromophore in Escherichia coli photolyase and Vibrio cholerae cryptochrome-1

Sokolova, O., Cecala, C., Gopal, A., Cortazar, F., McDowell-Buchanan, C., Sancar, A., Gindt, Y. M. & Schelvis, J. P. M., 27 Mar 2007, In : Biochemistry. 46, 12, p. 3673-3681 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Structural studies examining the substrate specificity profiles of PC-PLCBc protein variants

Benfield, A. P., Goodey, N. M., Phillips, L. T. & Martin, S. F., 1 Apr 2007, In : Archives of Biochemistry and Biophysics. 460, 1, p. 41-47 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3

Casares, S., Ab, E., Eshuis, H., Lopez-Mayorga, O., Van Nuland, N. A. J. & Conejero-Lara, F., 27 Apr 2007, In : BMC Structural Biology. 7, 22.

Research output: Contribution to journalArticle

22 Scopus citations
2006

A coumarin based fluorescent photoinduced electron transfer cation sensor

Kulatilleke, C. P., de Silva, S. A. & Eliav, Y., 11 Sep 2006, In : Polyhedron. 25, 13, p. 2593-2596 4 p.

Research output: Contribution to journalArticle

53 Scopus citations