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University profile
Dr. Alan L. Pehrson is an assistant professor in the Psychology Department and directs the Applied Neuropharmacology Laboratory at Montclair State University. Dr. Pehrson received a PhD in Biological Psychology from Virginia Commonwealth University, and completed postdoctoral fellowships with the Center for Neuroscience at the University of Pittsburgh and at Lundbeck, an industrial neuroscience firm.
Dr. Pehrson's research focuses on identifying and understanding biological mechanisms that can be used to improve symptoms associated with psychiatric disease, especially cognitive dysfunction and changes in mood. Dr. Pehrson is an author on 48 peer-reviewed articles in a variety of neuroscience and pharmacology journals, and was a key player in the development of the antidepressant vortioxetine (Trintellix).
Research interests
Identifying and understanding biological mechanisms that can be used to improve symptoms associated with psychiatric disease, especially cognitive dysfunction and changes in mood.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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Phencyclidine-induced Cognitive Impairments
National Institute of Mental Health
1/05/05 → 30/04/08
Project: Research
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The role of serotonin neurotransmission in rapid antidepressant actions
Pehrson, A. L., Roberts, D., Khawaja, A. & McNair, R., 2022, (Accepted/In press) In: Psychopharmacology.Research output: Contribution to journal › Review article › peer-review
9 Scopus citations -
Vortioxetine Reduces Marble Burying but only Transiently Enhances Social Interaction Preference in Adult Male BTBR T+Itpr3tf/J Mice
Witt, N. A., Lee, B., Ghent, K., Zhang, W. Q., Pehrson, A. L., Sánchez, C. & Gould, G. G., 16 Oct 2019, In: ACS Chemical Neuroscience. 10, 10, p. 4319-4327 9 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Acute effects of vortioxetine and duloxetine on resting-state functional connectivity in the awake rat
Pérez, P. D., Ma, Z., Hamilton, C., Sánchez, C., Mørk, A., Pehrson, A. L., Bundgaard, C. & Zhang, N., 1 Jan 2018, In: Neuropharmacology. 128, p. 379-387 9 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Effects of vortioxetine on biomarkers associated with glutamatergic activity in an SSRI insensitive model of depression in female rats
Hlavacova, N., Li, Y., Pehrson, A., Sanchez, C., Bermudez, I., Csanova, A., Jezova, D. & Franklin, M., 2 Mar 2018, In: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 82, p. 332-338 7 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Frontal cortex dysfunction as a target for remediation in opiate use disorder: Role in cognitive dysfunction and disordered reward systems
Roberts, D., Wolfarth, A., Sanchez, C. & Pehrson, A. L., 1 Jan 2018, Progress in Brain Research. O'Mara, S. (ed.). Elsevier B.V., p. 179-227 49 p. (Progress in Brain Research; vol. 239).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
6 Scopus citations