• 1207 Citations
  • 18 h-Index
1987 …2018
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Research Output 1987 2018

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Chapter
2017
1 Citation (Scopus)

Comprehensive Medicinal Chemistry III

Chackalamannil, S., Rotella, D. & Ward, S. E., 3 Jun 2017, The Future of Drug Discovery: Drug Discovery Technologies: In Silico Drug Discovery Tools: Experimental Adme and Toxicology: Cancer, Immunology and Inflammation, and Infectious Disease: Biologics Medicine: Cns, Pain, Metabolic Syndrome, Cardiovascular, Tissue Fibrosis and Urinary Incontinence: Case Histories in Recent Drug Discovery. Elsevier Inc., Vol. 1-8. p. 1-4369 4369 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Biological Products
Medicine
Bispecific Antibodies
Peptide Nucleic Acids
Molecules
2015
1 Citation (Scopus)

Serendipitous target-based drug discoveries

Fischer, J. & Rotella, D., 30 Jan 2015, Successful Drug Discovery. wiley, p. 3-18 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Drug Discovery
Citalopram
Omeprazole
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Pharmaceutical Preparations
2014

Recent Results In Phosphodiesterase Inhibitor Development and CNS Applications

Rotella, D., 28 Apr 2014, Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System: From Biology to Drug Discovery. Wiley Blackwell, p. 115-144 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Phosphodiesterase Inhibitors
Phosphoric Diester Hydrolases
Erectile Dysfunction
Nervous System Diseases
Psychiatry
2012

Pioneer and Analogue Drugs

Fischer, J., Ganellin, C. R. & Rotella, D. P., 18 Dec 2012, Analogue-Based Drug Discovery III. Wiley-VCH, p. 1-19 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Direct analogs
Dipeptidyl-Peptidase IV Inhibitors
Histamine H2 Antagonists
Serotonin Uptake Inhibitors
Angiotensin-Converting Enzyme Inhibitors
2010

Selective Serotonin Reuptake Inhibitors for the Treatment of Depression

Childers, W. E. & Rotella, D., 30 Aug 2010, Analogue-Based Drug Discovery II. Wiley-VCH, p. 269-295 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Norepinephrine Plasma Membrane Transport Proteins
Obsessive-Compulsive Disorder
Serotonin Uptake Inhibitors
2007
16 Citations (Scopus)

Chapter 1 Potential CNS Applications for Phosphodiesterase Enzyme Inhibitors

Brandon, N. J. & Rotella, D. P., 15 Nov 2007, Annual Reports in Medicinal Chemistry. Macor, J. (ed.). p. 3-12 10 p. (Annual Reports in Medicinal Chemistry; vol. 42).

Research output: Chapter in Book/Report/Conference proceedingChapter

Phosphodiesterase Inhibitors
Phosphoric Diester Hydrolases
Enzyme Inhibitors
Enzymes
Availability
2006
4 Citations (Scopus)

Phosphodiesterases

Rotella, D. P., 1 Nov 2006, Comprehensive Medicinal Chemistry II. Elsevier Ltd., Vol. 2. p. 919-957 39 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Phosphoric Diester Hydrolases