• 1239 Citations
  • 18 h-Index
1987 …2018

Research output per year

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Research Output

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Comment/debate
2012

Drug discovery 2012 and beyond

Rotella, D. P., 8 Mar 2012, In : ACS Medicinal Chemistry Letters. 3, 3, p. 172-173 2 p.

Research output: Contribution to journalComment/debate

5 Scopus citations
2000

A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats

Rotella, D. P., Wang, Z. Q., Zweier, J. L., Samouilov, A., Macarthur, H., Misko, T. P., Currie, M. G., Cuzzocrea, S., Sikorski, J. A. & Riley, D. P., 1 Apr 2000, In : Chemtracts. 13, 4, p. 253-255 3 p.

Research output: Contribution to journalComment/debate

Small-molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

Rotella, D. P., Kapoor, T. M., Haggarty, S. J., King, R. W., Schreiber, S. L. & Mitchison, T. J., 1 Apr 2000, In : Chemtracts. 13, 4, p. 256-258 3 p.

Research output: Contribution to journalComment/debate

1999

Photoaffinity labeling of oxidosqualene cyclase and squalene cyclase by a benzophenone-containing inhibitor

Abe, I., Zheng, Y. F., Prestwich, G. D. & Rotella, D. P., 1 Jan 1999, In : Chemtracts. 12, 7, p. 483-486 4 p.

Research output: Contribution to journalComment/debate

Reduced immunotoxicity and preservation of antibacterial activity in a releasable side-chain carbapenem antibiotic

Rosen, H., Hadju, R., Silver, L., Kropp, H., Dorso, K., Kohler, J., Sundelof, J. G., Huber, J., Hammond, G. G., Jackson, J. J., Gill, C. J., Thompson, R., Pelak, B. A., Epstein-Toney, J. H., Lankas, G., Wilkening, R. R., Wildonger, K. J., Blizzard, T. A., DiNinno, F. P., Ratcliffe, R. W. & 4 others, Heck, J. V., Kozarich, J. W., Hammond, M. L. & Rotella, D. P., 1 Aug 1999, In : Chemtracts. 12, 9, p. 675-678 4 p.

Research output: Contribution to journalComment/debate

Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K

Rotella, D. P., Yamashita, D. S., Oh, H. J., Uzinskas, I. N., Erhard, K. F., Allen, A. C., Haltiwanger, R. C., Zhao, B., Smith, W. W., Abdel-Meguid, S. S., Alessio, K. D., Jansen, C. A., McQueney, M. S., Tomoszek, T. A., Levy, M. A. & Veber, D. F., 1 Apr 1999, In : Chemtracts. 12, 4, p. 272-275 4 p.

Research output: Contribution to journalComment/debate

1998

Discovery of CGS 27023A, a nonpeptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits

Rotella, D. P., Bayburt, E. K., Capparelli, M. P., Carroll, B. J., Goldstein, R., Justice, M. R., Zhu, L., Hu, S., Melton, R. A., Freyer, L., Golding, R. L., Doughty, J. R., Spirito, S., Bloncuzzi, V., Wilson, D., Byrne, E. M., Ganu, V. & Parker, D. T., 1 Apr 1998, In : Chemtracts. 11, 4, p. 301-305 5 p.

Research output: Contribution to journalComment/debate

Orally active trifluoromethyl ketone inhibitors of human leukocyte elastase

Rotella, D. P., Bernstein, P. R., Bohnert, C. M., Brown, F. J., Bryant, C., Damewood, J. R., Early, R., Feeney, S. W., Edwards, P. D., Gomes, B., Hulsinger, J. M., Kosmider, B. J., Krell, R. D., Moore, G., Salcedo, T. W., Show, A., Silberstein, D. S., Steelman, G. B., Stein, M., Strimpler, A. & 5 others, Thomas, R. M., Vacek, E. P., Williams, J. C., Wolanin, D. J. & Woolson, S., 1 Jun 1998, In : Chemtracts. 11, 7, p. 546-549 4 p.

Research output: Contribution to journalComment/debate

1 Scopus citations