• 1207 Citations
  • 18 h-Index
1987 …2018
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1987 2018

Filter
Review article
2014
74 Citations (Scopus)

Progress in the discovery and development of heat shock protein 90 (Hsp90) inhibitors

Bhat, R., Tummalapalli, S. R. & Rotella, D. P., 13 Nov 2014, In : Journal of Medicinal Chemistry. 57, 21, p. 8718-8728 11 p.

Research output: Contribution to journalReview article

HSP90 Heat-Shock Proteins
Protein Isoforms
Clinical Trials
Research
Proteins
2013
8 Citations (Scopus)

The discovery and development of boceprevir

Rotella, D. P., 1 Nov 2013, In : Expert Opinion on Drug Discovery. 8, 11, p. 1439-1447 9 p.

Research output: Contribution to journalReview article

Peptide Hydrolases
Peptidomimetics
Therapeutics
Ribavirin
Expert Testimony
2012
15 Citations (Scopus)

Recent results in protein kinase inhibition for tropical diseases

Rotella, D., 15 Nov 2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 22, p. 6788-6793 6 p.

Research output: Contribution to journalReview article

Protein Kinases
Parasitic Diseases
Leishmaniasis
Enzyme Inhibitors
Malaria
2004
11 Citations (Scopus)

SB-480848 (GlaxoSmithKline)

Rotella, D. P., 1 Mar 2004, In : Current Opinion in Investigational Drugs. 5, 3, p. 348-351 4 p.

Research output: Contribution to journalReview article

1-Alkyl-2-acetylglycerophosphocholine Esterase
Atherosclerosis
SB-480848
2003
9 Citations (Scopus)

Tadalafil Lilly ICOS

Rotella, D., 1 Jan 2003, In : Current Opinion in Investigational Drugs. 4, 1, p. 60-65 6 p.

Research output: Contribution to journalReview article

3',5'-Cyclic-GMP Phosphodiesterases
Carbolines
Phase III Clinical Trials
Phase II Clinical Trials
Clinical Trials, Phase I
2002
16 Citations (Scopus)

Osteoporosis: Challenges and new opportunities for therapy

Rotella, D. P., 1 Jul 2002, In : Current Opinion in Drug Discovery and Development. 5, 4, p. 477-486 10 p.

Research output: Contribution to journalReview article

Osteoporosis
Integrin alphaVbeta3
Cathepsin K
Calcium-Sensing Receptors
Hydroxymethylglutaryl-CoA Reductase Inhibitors
221 Citations (Scopus)

Phosphodiesterase 5 inhibitors: Current status and potential applications

Rotella, D. P., 1 Sep 2002, In : Nature Reviews Drug Discovery. 1, 9, p. 674-682 9 p.

Research output: Contribution to journalReview article

Phosphodiesterase 5 Inhibitors
Type 5 Cyclic Nucleotide Phosphodiesterases
Pharmaceutical Chemistry
Phosphoric Diester Hydrolases
Erectile Dysfunction
2001
23 Citations (Scopus)

Phosphodiesterase type 5 inhibitors: Discovery and therapeutic utility

Rotella, D. P., 5 May 2001, In : Drugs of the Future. 26, 2, p. 153-162 10 p.

Research output: Contribution to journalReview article

Phosphodiesterase 5 Inhibitors
Therapeutics
1999

Drug discovery and development

Finney, N., Ghosh, S., Hirst, J., Norman, P., Rotella, D. & Williams, M., 14 Apr 1999, In : Current Opinion in Drug Discovery and Development. 2, 2, p. 71-80 10 p.

Research output: Contribution to journalReview article

Drug Discovery