David Talaga

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David Talaga

 https://orcid.org/0000-0002-8341-2603
Calculated based on number of publications stored in Pure and citations from Scopus
1985 …2015

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Personal profile

University profile

Dr. David Talaga received his undergraduate degree in chemistry and mathematics from Occidental College and supplemented his interests with graduate courses from Caltech. He started a volunteer tutoring program that significantly increased the number of students show could receive extra help in chemistry and biology. These efforts also enhanced the interaction between student in the earlier and later years of their undergraduate experience. These experiences cemented his interest in research and teaching in physical chemistry.

Dr. Talaga's research program focuses on the heterogeneity in protein conformation, particularly as proteins aggregate into various intermediates that lead to amyloid formation. His research group develops measurements that can distinguish protein conformation through different aggregation states. A significant part of their efforts includes solving experimental and theoretical challenges that arise in measuring and interpreting such heterogeneous systems. These problems not only confound characterization of amyloidogenesis, but also appear in most protein systems, making these ancillary developments important to many other fields.

Research Interests

Protein Folding, Protein and Peptide Conformational Dynamics, Protein Aggregation, Amyloid, Parkinson’s Disease, Amyloidoses, Nanopores, Single Molecule Fluorescence, Ultrafast Spectroscopy, Information Theory, Bayesian Statistics, Global Data Analysis, Statistical Mechanics.

Teaching

General Chemistry, Analytical Chemistry, Physical Chemistry, Spectroscopy, Group Theory, Statistical Mechanics, Statistical Thermodynamics, Biophysical Chemistry, General Education Chemistry.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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  • INTERFACIALLY ACTIVATED AGGREGATION OF ALPHA-SYNUCLEIN

    Talaga, D.

    National Institute of Health (NIH)

    15/03/15 → 28/02/18

    Project: Research

  • NIRT: Ligand Nanodisplay for Cellular Internalization and Super-Activation

    Moghe, P. P. V., Talaga, D., Tsakalakos, T. T., Roth, C. C. M. & Schwarzbauer, J. J.

    National Science Foundation

    1/09/06 → 31/08/12

    Project: Research

  • New statistical tools for single molecule experiments

    Talaga, D. & Talaga, D. S.

    National Institute of General Medical Sciences

    1/08/04 → 31/01/11

    Project: Research

  • TRANSIENT INFRARED SPECTROSCOPY

    Volk, M., Hochstrasser, R. M., Volk, M. M. & Talaga, D.

    National Center for Research Resources

    1/10/95 → 30/09/99

    Project: Research

  • ULTRAFAST OPTICAL PROCESSES LABORATORY

    Hochstrasser, R. M., Cashmore, A. A. R., Adachi, N. K., Loh, A. A. P., Johnson, A. A. T., Anni, E., Aprelev, A., Arnold, E., Asplund, N. M., Axelsen, P. H., Smith, A. A. B., Garcia, A. A. E., Cooperman, B. B. S., Barkley, N. M. D., Cooperman, B. B. S., Bayer, N. M., Berry, N. D., Birnbaum, N. E. R., Blasie, K. J., Boesze-battaglia, N. K., Brewer, S. H., Chance, B. B., Hudson, B. B. S., Burdick, J. A., Burgess, K., Pastrana-rios, B. B., Packard, B. B., Stubbs, C. C., Galli, C. C. J., Phillips, C. C. M., Callender, N. R., Longergan, C. C., Cashmore, N. A. R., Crouch, C. C., Chaiken, I. M., Chance, M., Cheung, N. R., Cooperman, N. B. S., Crocker, J. C., Deutsch, C. C. J., Koshland, D. D. E., Dai, H., Dan, N., Rusak, D. D., Ash, D. D. E., DeGrado, W. F., Degrado, N. W. F., Depaula, N. J., Deutsch, C. J., Dinter-gottlieb, N. G., Dmochowski, I. J., Dutton, L. P., Birnbaum, E. E. R., Ebright, N. R. H., Arnold, E. E., Ellis-davies, N. G., Boder, E. E. T., Gai, F. F., Fierke, N. C., Dahlquist, F. F. W., Haran, G. G., Gai, F., Galli, N. C. J., Ellis-davies, G. G., Roder, H. H., Scheraga, H. H., Dai, H. H., Haran, N. G., Roder, H. H., Hochstrasser, R. M., Holtom, N. G. R., Hudson, B. S., Chen, I. I., Ikeda-saito, N. M., Ishii, N. M., Dmochowski, I. I. J., Jain, N. A., Kelley, J. J. A., Saven, J. J. G., Jia, N. Y., Karp, J. J. S., Weisel, J. J. W., Zubieta, J. J. A., Johansson, J. J. S., Wayne, J. J. E., Vanderkooi, J. J. M., Fang, J. J., Sanger, J. J. W., Adachi, K. K., Boesze-battaglia, K. K., Karp, J. S., Kelley, J. A., Burgess, K. K., Koshland, N. D. E., Krishnaswamy, S., Kumble, N. R., Parkhurst, L. L., Liebman, N. P. A., Lim, M., Lu, N. P., Ludescher, N. R. D., Rivera, L. L. A., Regan, L. L. J., Peteanu, L. L. A., Bayer, M. M., Ikeda-saito, M. M., Ishii, M. M., Volk, M. M., Therien, M. M. J., Lim, M. M., Bruist, M. M. F., Therien, M. M. J., Michel-beyerle, N. M. E., Lee, M. M., Morlino, N. E. A., Chance, M. M., Mukamel, S., Scherer, N. N., Nakanishi, N. K., Nanda, V., Dan, N. N., Lu, P. P., Liebman, P. P. A., Park, S., Parkhurst, N. L., Pasternack, N. R., Pestka, S., Dutton, P. P. L., Petersson, E. J., Petska, N. S., Phillips, N. C. M., Axelsen, P. P. H., Callender, R. R., Cogdell, R. R., Weiss, R. R., Ludescher, R. R. D., Ebright, R. R. H., Raleigh, D. P., Righini, R. R., Hochstrasser, R. R. M., Roder, N. H., Fairman, R. R., Gellman, S. S. H., Sarkar, C., Saven, J. G., Scheraga, N. H., Scherer, N. N., Vinogradov, S. S., Pestka, S. S., Regen, S. S. L., White, S. S. A., Decatur, S. S. M., Park, S. S., Krishnaswamy, S. S., Dougherty, T. T., Yonetani, T. T., Talaga, D., Therien, M. J., Therien, N. M. J., Spiro, T. T. G., Topp, M. R., Vanderkooi, J. M., Vinogradov, S., Volk, N. M., Degrado, W. W. F., Wayne, J. E., Degrado, W. W. F., Winkelstein, B. A., Jia, Y. Y., Yonetani, T., Getahun, Z. Z., Mourelatos, Z. Z., Adachi, K., Ash, D. E., Axelsen, P., Bayer, M., Birnbaum, E., Chance, M., Degrado, W., Dougherty, T., Ebright, R., Galli, C., Gunner, M., Haran, G., Ishii, M., Jia, Y., Koshland, D., Kumble, R., Lu, P., Ludescher, R., Phillips, C., Roder, H., Scherer, N., Stubbs, C., Swager, T., Therien, M., Volk, M., Walters, V. & Weiss, N. R.

    1/08/85 → 31/05/12

    Project: Research

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