Find Research Outputs

Search in all content

Filters for Research Output

Search concepts
Selected Filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016

Author

  • Alan Pehrson
2019

Vortioxetine Reduces Marble Burying but only Transiently Enhances Social Interaction Preference in Adult Male BTBR T+Itpr3tf/J Mice

Witt, N. A., Lee, B., Ghent, K., Zhang, W. Q., Pehrson, A. L., Sánchez, C. & Gould, G. G., 16 Oct 2019, In : ACS Chemical Neuroscience. 10, 10, p. 4319-4327 9 p.

Research output: Contribution to journalArticle

2018

Acute effects of vortioxetine and duloxetine on resting-state functional connectivity in the awake rat

Pérez, P. D., Ma, Z., Hamilton, C., Sánchez, C., Mørk, A., Pehrson, A. L., Bundgaard, C. & Zhang, N., 1 Jan 2018, In : Neuropharmacology. 128, p. 379-387 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Effects of vortioxetine on biomarkers associated with glutamatergic activity in an SSRI insensitive model of depression in female rats

Hlavacova, N., Li, Y., Pehrson, A., Sanchez, C., Bermudez, I., Csanova, A., Jezova, D. & Franklin, M., 2 Mar 2018, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 82, p. 332-338 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Frontal cortex dysfunction as a target for remediation in opiate use disorder: Role in cognitive dysfunction and disordered reward systems

Roberts, D., Wolfarth, A., Sanchez, C. & Pehrson, A. L., 1 Jan 2018, Progress in Brain Research. O'Mara, S. (ed.). Elsevier B.V., p. 179-227 49 p. (Progress in Brain Research; vol. 239).

Research output: Chapter in Book/Report/Conference proceedingChapter

The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT 3 receptor expressing interneurons: An in vitro study in rat hippocampus slices

Dale, E., Grunnet, M., Pehrson, A. L., Frederiksen, K., Larsen, P. H., Nielsen, J., Stensbøl, T. B., Ebert, B., Yin, H., Lu, D., Liu, H., Jensen, T. N., Yang, C. R. & Sanchez, C., 15 Jun 2018, In : Brain Research. 1689, p. 1-11 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Vortioxetine differentially modulates MK-801-induced changes in visual signal detection task performance and locomotor activity

Hillhouse, T. M., Merritt, C. R., Smith, D. A., Cajina, M., Sanchez, C., Porter, J. H. & Pehrson, A. L., 13 Sep 2018, In : Frontiers in Pharmacology. 9, SEP, 1024.

Research output: Contribution to journalArticle

Open Access

Vortioxetine improves context discrimination in mice through a neurogenesis independent mechanism

Felice, D., Guilloux, J. P., Pehrson, A., Li, Y., Mendez-David, I., Gardier, A. M., Sanchez, C. & David, D. J., 12 Mar 2018, In : Frontiers in Pharmacology. 9, MAR, 204.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
Open Access
5 Scopus citations
2017

A study of time- and sex-dependent effects of vortioxetine on rat sexual behavior: Possible roles of direct receptor modulation

Li, Y., Pehrson, A. L., Oosting, R. S., Gulinello, M., Olivier, B. & Sanchez, C., 15 Jul 2017, In : Neuropharmacology. 121, p. 89-99 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Chronic vortioxetine treatment in rodents modulates gene expression of neurodevelopmental and plasticity markers

Waller, J. A., Tamm, J. A., Abdourahman, A., Pehrson, A. L., Li, Y., Cajina, M. & Sánchez, C., 1 Feb 2017, In : European Neuropsychopharmacology. 27, 2, p. 192-203 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Impact of vortioxetine on synaptic integration in prefrontal-subcortical circuits: Comparisons with escitalopram

Chakroborty, S., Geisbush, T. R., Dale, E., Pehrson, A. L., Sánchez, C. & West, A. R., 26 Oct 2017, In : Frontiers in Pharmacology. 8, OCT, 764.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

In vivo and in vitro effects of vortioxetine on molecules associated with neuroplasticity

Kugathasan, P., Waller, J., Westrich, L., Abdourahman, A., Tamm, J. A., Pehrson, A. L., Dale, E., Gulinello, M., Sanchez, C. & Li, Y., 1 Mar 2017, In : Journal of Psychopharmacology. 31, 3, p. 365-376 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Neuroplasticity pathways and protein-interaction networks are modulated by vortioxetine in rodents

Waller, J. A., Nygaard, S. H., Li, Y., Jardin, K. G., Tamm, J. A., Abdourahman, A., Elfving, B., Pehrson, A. L., Sánchez, C. & Wernersson, R., 4 Aug 2017, In : BMC Neuroscience. 18, 1, 56.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Serotonin Transporter-Independent Actions of the Antidepressant Vortioxetine As Revealed Using the SERT Met172 Mouse

Nackenoff, A. G., Simmler, L. D., Baganz, N. L., Pehrson, A. L., Sánchez, C. & Blakely, R. D., 17 May 2017, In : ACS Chemical Neuroscience. 8, 5, p. 1092-1100 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Discriminative stimulus properties of 1.25 mg/kg clozapine in rats: Mediation by serotonin 5-HT2 and dopamine D4 receptors

Prus, A. J., Wise, L. E., Pehrson, A. L., Philibin, S. D., Bang-Andersen, B., Arnt, J. & Porter, J. H., 1 Oct 2016, In : Brain Research. 1648, p. 298-305 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Effects of serotonin in the hippocampus: How SSRIs and multimodal antidepressants might regulate pyramidal cell function

Dale, E., Pehrson, A. L., Jeyarajah, T., Li, Y., Leiser, S. C., Smagin, G., Olsen, C. K. & Sanchez, C., 1 Apr 2016, In : CNS Spectrums. 21, 2, p. 143-161 19 p.

Research output: Contribution to journalReview article

Open Access
50 Scopus citations

Histamine may contribute to vortioxetine's procognitive effects; possibly through an orexigenic mechanism

Smagin, G. N., Song, D., Budac, D. P., Waller, J. A., Li, Y., Pehrson, A. L. & Sánchez, C., 4 Jul 2016, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 68, p. 25-30 6 p.

Research output: Contribution to journalShort survey

4 Scopus citations
16 Scopus citations

Task-and treatment length-dependent effects of vortioxetine on scopolamine-induced cognitive dysfunction and hippocampal extracellular acetylcholine in rats

Pehrson, A. L., Hillhouse, T. M., Haddjeri, N., Rovera, R., Porter, J. H., Mørk, A., Smagin, G., Song, D., Budac, D., Cajina, M. & Sanchez, C., Sep 2016, In : Journal of Pharmacology and Experimental Therapeutics. 358, 3, p. 472-482 11 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations