A motor relay on ciliary tracks

Robert O'Hagan, Maureen M. Barr

Research output: Contribution to journalArticle

Abstract

A powerful combination of two-colour imaging in vivo, Fourier-filtered kymography and simulations provides a high-resolution view of kinesin-2 transport dynamics in cilia. This study reveals heterotrimeric kinesin-II as an 'obstacle-course runner' and homodimeric OSM-3 (KIF17) as a 'long-distance runner', and elucidates the 'baton handoff' between these two kinesin-2 motors on the microtubule track.

Original languageEnglish
Pages (from-to)1517-1519
Number of pages3
JournalNature Cell Biology
Volume17
Issue number12
DOIs
StatePublished - 27 Nov 2015

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