A motor relay on ciliary tracks

Robert O'Hagan, Maureen M. Barr

Research output: Contribution to journalArticleResearchpeer-review

Abstract

A powerful combination of two-colour imaging in vivo, Fourier-filtered kymography and simulations provides a high-resolution view of kinesin-2 transport dynamics in cilia. This study reveals heterotrimeric kinesin-II as an 'obstacle-course runner' and homodimeric OSM-3 (KIF17) as a 'long-distance runner', and elucidates the 'baton handoff' between these two kinesin-2 motors on the microtubule track.

Original languageEnglish
Pages (from-to)1517-1519
Number of pages3
JournalNature Cell Biology
Volume17
Issue number12
DOIs
StatePublished - 27 Nov 2015

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Kinesin
Kymography
Cilia
Microtubules
Color
kinesin-II

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O'Hagan, Robert ; Barr, Maureen M. / A motor relay on ciliary tracks. In: Nature Cell Biology. 2015 ; Vol. 17, No. 12. pp. 1517-1519.
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A motor relay on ciliary tracks. / O'Hagan, Robert; Barr, Maureen M.

In: Nature Cell Biology, Vol. 17, No. 12, 27.11.2015, p. 1517-1519.

Research output: Contribution to journalArticleResearchpeer-review

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