A motor relay on ciliary tracks

Robert O'Hagan; Maureen M. Barr

doi:10.1038/ncb3279

A motor relay on ciliary tracks

Robert O'Hagan, Maureen M. Barr

Biology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A powerful combination of two-colour imaging in vivo, Fourier-filtered kymography and simulations provides a high-resolution view of kinesin-2 transport dynamics in cilia. This study reveals heterotrimeric kinesin-II as an 'obstacle-course runner' and homodimeric OSM-3 (KIF17) as a 'long-distance runner', and elucidates the 'baton handoff' between these two kinesin-2 motors on the microtubule track.

Original language	English
Pages (from-to)	1517-1519
Number of pages	3
Journal	Nature Cell Biology
Volume	17
Issue number	12
DOIs	https://doi.org/10.1038/ncb3279
State	Published - 27 Nov 2015

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abstract = "A powerful combination of two-colour imaging in vivo, Fourier-filtered kymography and simulations provides a high-resolution view of kinesin-2 transport dynamics in cilia. This study reveals heterotrimeric kinesin-II as an 'obstacle-course runner' and homodimeric OSM-3 (KIF17) as a 'long-distance runner', and elucidates the 'baton handoff' between these two kinesin-2 motors on the microtubule track.",

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A motor relay on ciliary tracks

Abstract

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