Application of Chimera grid to modelling cell motion and aggregation in a narrow tube

B. Chung, P. C. Johnson, A. S. Popel

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

A computational scheme using the Chimera grid method is presented for simulation of three-dimensional motion and aggregation of two red blood cells (RBCs) in a narrow tube. The cells are modelled as rigid ellipsoidal particles; the computational scheme is applicable to deformable fluid-filled particles. Attractive energy between two RBCs is modelled by a depletion interaction theory and used for simulating aggregation of two cells. Through the simulation, we show that the Chimera grid method is applicable to the simulation of three-dimensional motion and aggregation of multiple RBCs in a microvessel and microvascular network.

Original languageEnglish
Pages (from-to)105-128
Number of pages24
JournalInternational Journal for Numerical Methods in Fluids
Volume53
Issue number1
DOIs
StatePublished - 10 Jan 2007

Fingerprint

Red Blood Cells
Aggregation
Tube
Blood
Agglomeration
Grid
Motion
Cell
Modeling
Three-dimensional
Simulation
Depletion
Cells
Fluid
Fluids
Energy
Interaction

Keywords

  • Chimera grid
  • Depletion interaction energy
  • RBC aggregation
  • Red blood cell

Cite this

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Application of Chimera grid to modelling cell motion and aggregation in a narrow tube. / Chung, B.; Johnson, P. C.; Popel, A. S.

In: International Journal for Numerical Methods in Fluids, Vol. 53, No. 1, 10.01.2007, p. 105-128.

Research output: Contribution to journalArticle

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