TY - JOUR
T1 - Basic reinfection number and backward bifurcation
AU - Song, Baojun
N1 - Publisher Copyright:
© 2021 American Institute of Mathematical Sciences. All rights reserved.
PY - 2021
Y1 - 2021
N2 - Some epidemiological models exhibit bi-stable dynamics even when the basic reproduction number R0 is below 1, through a phenomenon known as a backward bifurcation. Causes for this phenomenon include exogenous reinfection, super-infection, relapse, vaccination exercises, heterogeneity among subpopulations, etc. To measure the reinfection forces, this paper defines a second threshold: the basic reinfection number. This number characterizes the type of bifurcation when the basic reproduction number is equal to one. If the basic reinfection number is greater than one, the bifurcation is backward. Otherwise it is forward. The basic reinfection number with the basic reproduction number together gives a complete measure for disease control whenever reinfections (or relapses) matter. We formulate the basic reinfection number for a variety of epidemiological models.
AB - Some epidemiological models exhibit bi-stable dynamics even when the basic reproduction number R0 is below 1, through a phenomenon known as a backward bifurcation. Causes for this phenomenon include exogenous reinfection, super-infection, relapse, vaccination exercises, heterogeneity among subpopulations, etc. To measure the reinfection forces, this paper defines a second threshold: the basic reinfection number. This number characterizes the type of bifurcation when the basic reproduction number is equal to one. If the basic reinfection number is greater than one, the bifurcation is backward. Otherwise it is forward. The basic reinfection number with the basic reproduction number together gives a complete measure for disease control whenever reinfections (or relapses) matter. We formulate the basic reinfection number for a variety of epidemiological models.
KW - Basic reinfection number
KW - Bifurcation
KW - Differential equations
KW - Disease dynamics
UR - http://www.scopus.com/inward/record.url?scp=85115444171&partnerID=8YFLogxK
U2 - 10.3934/mbe.2021400
DO - 10.3934/mbe.2021400
M3 - Article
C2 - 34814289
AN - SCOPUS:85115444171
SN - 1547-1063
VL - 18
SP - 8064
EP - 8083
JO - Mathematical Biosciences and Engineering
JF - Mathematical Biosciences and Engineering
IS - 6
ER -