Keyphrases
Alzheimer's Disease
20%
Anxiety-depression
20%
Biochemical Mechanism
20%
Cell Surface Receptor
20%
Cell-based
20%
Cellular Models
20%
Clinical Validation
20%
CNS Disorders
40%
CNS Drugs
20%
Cyclic GMP
20%
Direct Interaction
20%
Disease Process
20%
Drug Target
20%
Drug-like
20%
Enzyme Inhibitors
100%
Genetic Linkage
20%
Human Trials
40%
Inhibitor Development
20%
Intracellular Signaling
20%
Medical Needs
20%
Nuclear Receptor
20%
PDE
100%
PDE Inhibitors
100%
PDE2
20%
PDE4 Inhibitor
20%
Phosphodiesterase
100%
Phosphodiesterase Inhibition
20%
Potential Therapeutics
20%
Preclinical Validation
20%
Rational Design
20%
Receptor Mechanisms
20%
Receptor-based
20%
Schizophrenia Depression
20%
Second Messenger
20%
Selective Inhibitor
20%
Selectivity Issues
20%
Signal Transduction Pathway
20%
Structural Class
20%
Structural Diversity
20%
Subcellular Distribution
20%
Target Interaction
20%
Target Selectivity
20%
Therapeutic Approaches
20%
Therapeutic Utility
20%
Treatment Mechanisms
20%
X-ray Crystal Structure
20%
Pharmacology, Toxicology and Pharmaceutical Science
Alzheimer's Disease
25%
Cell Nucleus Receptor
25%
Cell Surface Receptor
25%
Clinical Study
25%
Cyclic GMP
25%
Diseases
50%
Enzyme Inhibitor
100%
Phosphodiesterase
100%
Phosphodiesterase IV Inhibitor
25%
Receptor
50%
Biochemistry, Genetics and Molecular Biology
Cyclic Guanosine Monophosphate
25%
Neuroscience
Cyclic Guanosine Monophosphate
25%