Abstract
We have acquired 2-D and 3-D microwave tomographic images of the calcaneus bones of two patients to assess correlation of the microwave properties with X-ray density measures. The two volunteers were selected because each had one leg immobilized for at least six weeks during recovery from a lower leg injury. A soft-prior regularization technique was incorporated with the microwave imaging to quantitatively assess the bulk dielectric properties within the bone region. Good correlation was observed between both permittivity and conductivity and the computed tomography-derived density measures. These results represent the first clinical examples of microwave images of the calcaneus and some of the first 3-D tomographic images of any anatomical site in the living human.
| Original language | English |
|---|---|
| Article number | 6242390 |
| Pages (from-to) | 3304-3313 |
| Number of pages | 10 |
| Journal | IEEE Transactions on Biomedical Engineering |
| Volume | 59 |
| Issue number | 12 |
| DOIs | |
| State | Published - 10 Dec 2012 |
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Keywords
- Bone
- bone density
- dielectric properties
- fracture risk
- microwave imaging
- osteoporosis
Cite this
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Clinical microwave tomographic imaging of the calcaneus : A first-in-human case study of two subjects. / Meaney, Paul M.; Goodwin, Douglas; Golnabi, Amir; Zhou, Tian; Pallone, Matthew; Geimer, Shireen D.; Burke, Gregory; Paulsen, Keith D.
In: IEEE Transactions on Biomedical Engineering, Vol. 59, No. 12, 6242390, 10.12.2012, p. 3304-3313.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Clinical microwave tomographic imaging of the calcaneus
T2 - A first-in-human case study of two subjects
AU - Meaney, Paul M.
AU - Goodwin, Douglas
AU - Golnabi, Amir
AU - Zhou, Tian
AU - Pallone, Matthew
AU - Geimer, Shireen D.
AU - Burke, Gregory
AU - Paulsen, Keith D.
PY - 2012/12/10
Y1 - 2012/12/10
N2 - We have acquired 2-D and 3-D microwave tomographic images of the calcaneus bones of two patients to assess correlation of the microwave properties with X-ray density measures. The two volunteers were selected because each had one leg immobilized for at least six weeks during recovery from a lower leg injury. A soft-prior regularization technique was incorporated with the microwave imaging to quantitatively assess the bulk dielectric properties within the bone region. Good correlation was observed between both permittivity and conductivity and the computed tomography-derived density measures. These results represent the first clinical examples of microwave images of the calcaneus and some of the first 3-D tomographic images of any anatomical site in the living human.
AB - We have acquired 2-D and 3-D microwave tomographic images of the calcaneus bones of two patients to assess correlation of the microwave properties with X-ray density measures. The two volunteers were selected because each had one leg immobilized for at least six weeks during recovery from a lower leg injury. A soft-prior regularization technique was incorporated with the microwave imaging to quantitatively assess the bulk dielectric properties within the bone region. Good correlation was observed between both permittivity and conductivity and the computed tomography-derived density measures. These results represent the first clinical examples of microwave images of the calcaneus and some of the first 3-D tomographic images of any anatomical site in the living human.
KW - Bone
KW - bone density
KW - dielectric properties
KW - fracture risk
KW - microwave imaging
KW - osteoporosis
UR - http://www.scopus.com/inward/record.url?scp=84870495964&partnerID=8YFLogxK
U2 - 10.1109/TBME.2012.2209202
DO - 10.1109/TBME.2012.2209202
M3 - Article
VL - 59
SP - 3304
EP - 3313
JO - IEEE Transactions on Biomedical Engineering
JF - IEEE Transactions on Biomedical Engineering
SN - 0018-9294
IS - 12
M1 - 6242390
ER -