Clinical microwave tomographic imaging of the calcaneus: A first-in-human case study of two subjects

Paul M. Meaney, Douglas Goodwin, Amir H. Golnabi, Tian Zhou, Matthew Pallone, Shireen D. Geimer, Gregory Burke, Keith D. Paulsen

Research output: Contribution to journalArticlepeer-review

59 Scopus citations

Abstract

We have acquired 2-D and 3-D microwave tomographic images of the calcaneus bones of two patients to assess correlation of the microwave properties with X-ray density measures. The two volunteers were selected because each had one leg immobilized for at least six weeks during recovery from a lower leg injury. A soft-prior regularization technique was incorporated with the microwave imaging to quantitatively assess the bulk dielectric properties within the bone region. Good correlation was observed between both permittivity and conductivity and the computed tomography-derived density measures. These results represent the first clinical examples of microwave images of the calcaneus and some of the first 3-D tomographic images of any anatomical site in the living human.

Original languageEnglish
Article number6242390
Pages (from-to)3304-3313
Number of pages10
JournalIEEE Transactions on Biomedical Engineering
Volume59
Issue number12
DOIs
StatePublished - 10 Dec 2012

Keywords

  • Bone
  • bone density
  • dielectric properties
  • fracture risk
  • microwave imaging
  • osteoporosis

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