Clinical microwave tomographic imaging of the calcaneus: A first-in-human case study of two subjects

Paul M. Meaney; Douglas Goodwin; Amir H. Golnabi; Tian Zhou; Matthew Pallone; Shireen D. Geimer; Gregory Burke; Keith D. Paulsen

doi:10.1109/TBME.2012.2209202

Clinical microwave tomographic imaging of the calcaneus: A first-in-human case study of two subjects

Paul M. Meaney, Douglas Goodwin, Amir H. Golnabi, Tian Zhou, Matthew Pallone, Shireen D. Geimer, Gregory Burke, Keith D. Paulsen

Applied Mathematics and Statistics

Research output: Contribution to journal › Article

55 Scopus citations

Abstract

We have acquired 2-D and 3-D microwave tomographic images of the calcaneus bones of two patients to assess correlation of the microwave properties with X-ray density measures. The two volunteers were selected because each had one leg immobilized for at least six weeks during recovery from a lower leg injury. A soft-prior regularization technique was incorporated with the microwave imaging to quantitatively assess the bulk dielectric properties within the bone region. Good correlation was observed between both permittivity and conductivity and the computed tomography-derived density measures. These results represent the first clinical examples of microwave images of the calcaneus and some of the first 3-D tomographic images of any anatomical site in the living human.

Original language	English
Article number	6242390
Pages (from-to)	3304-3313
Number of pages	10
Journal	IEEE Transactions on Biomedical Engineering
Volume	59
Issue number	12
DOIs	https://doi.org/10.1109/TBME.2012.2209202
State	Published - 10 Dec 2012

Keywords

Bone
bone density
dielectric properties
fracture risk
microwave imaging
osteoporosis

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10.1109/TBME.2012.2209202

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Meaney, P. M., Goodwin, D., Golnabi, A. H., Zhou, T., Pallone, M., Geimer, S. D., Burke, G., & Paulsen, K. D. (2012). Clinical microwave tomographic imaging of the calcaneus: A first-in-human case study of two subjects. IEEE Transactions on Biomedical Engineering, 59(12), 3304-3313. [6242390]. https://doi.org/10.1109/TBME.2012.2209202

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abstract = "We have acquired 2-D and 3-D microwave tomographic images of the calcaneus bones of two patients to assess correlation of the microwave properties with X-ray density measures. The two volunteers were selected because each had one leg immobilized for at least six weeks during recovery from a lower leg injury. A soft-prior regularization technique was incorporated with the microwave imaging to quantitatively assess the bulk dielectric properties within the bone region. Good correlation was observed between both permittivity and conductivity and the computed tomography-derived density measures. These results represent the first clinical examples of microwave images of the calcaneus and some of the first 3-D tomographic images of any anatomical site in the living human.",

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Clinical microwave tomographic imaging of the calcaneus : A first-in-human case study of two subjects. / Meaney, Paul M.; Goodwin, Douglas; Golnabi, Amir H.; Zhou, Tian; Pallone, Matthew; Geimer, Shireen D.; Burke, Gregory; Paulsen, Keith D.

In: IEEE Transactions on Biomedical Engineering, Vol. 59, No. 12, 6242390, 10.12.2012, p. 3304-3313.

Research output: Contribution to journal › Article

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