Controlling wound healing through debridement

M. A. Jones, B. Song, D. M. Thomas

Research output: Contribution to journalArticle

44 Scopus citations

Abstract

The formation of slough (dead tissue) on a wound is widely accepted as an inhibitor to natural wound healing. In this article, a system of differential equations that models slough/wound interaction is developed. We prove a threshold theorem that provides conditions on the amount of slough to guarantee wound healing. As a state-dependent time scale, debridement (the periodic removal of slough) is used as a control. We show that closure of the wound can be reached in infinite time by debriding.

Original languageEnglish
Pages (from-to)1057-1064
Number of pages8
JournalMathematical and Computer Modelling
Volume40
Issue number9-10
DOIs
StatePublished - Nov 2004

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