Depression and Substance Use: A Temporal-Ordered Model

Celia C. Lo, Tyrone C. Cheng, Iván A. De La Rosa

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background and Objectives: This study sought empirical evidence for the self-medication hypothesis. It asked whether diagnosis of depression, together with the use of mental-health care, leads to substance use. Methods: Data came from the 5-wave, longitudinal Fragile Families and Child Wellbeing (FFCW) Study, an investigation of a cohort of nearly 5,000 births, which oversampled non-marital births. FFCW examined newborns biological mothers and fathers, all of whom lived in the United States. The adults were initially interviewed between 1998 and 2000 (the period of the cohort's births); they were then re-interviewed for four times over 10 years. FFCW measured mental health-related variables, level of drug use, and social structural and demographic factors, all of which are also measured by the present study. Respondents in our study's two final subsamples had responded to every FFCW interview item we would use in constructing our final model's variables. Our subsample of mothers totaled 3,477 women, from whom 5,987 person-waves were derived. Our subsample of fathers totaled 2,096 men, yielding 3,543 person-waves. Results: We used STATA generalized estimating equations for panel data, and found some evidence to support the self-medication hypothesis. In addition, our results indicated that the relationship of substance use to the use of mental-health care was gender-specific. Conclusions/Importance: Empirical evidence from this study only partially supported the self-medication hypothesis; the co-occurrence of depression and substance abuse in our sample was also reflective of social structural and demographic variables and of prior substance use variables.

Original languageEnglish
Pages (from-to)1274-1283
Number of pages10
JournalSubstance Use and Misuse
Volume50
Issue number10
DOIs
StatePublished - 24 Aug 2015

Fingerprint

self-medication
Self Medication
Depression
Mental Health
mental health
Parturition
Fathers
father
Mothers
Demography
health care
Delivery of Health Care
evidence
human being
demographic factors
substance abuse
Substance-Related Disorders
drug use
Newborn Infant
Interviews

Keywords

  • self-medication hypothesis
  • substance use
  • temporal-ordered model

Cite this

Lo, Celia C. ; Cheng, Tyrone C. ; De La Rosa, Iván A. / Depression and Substance Use : A Temporal-Ordered Model. In: Substance Use and Misuse. 2015 ; Vol. 50, No. 10. pp. 1274-1283.
@article{0faf92cd5bfd45c49369d127df3dee1f,
title = "Depression and Substance Use: A Temporal-Ordered Model",
abstract = "Background and Objectives: This study sought empirical evidence for the self-medication hypothesis. It asked whether diagnosis of depression, together with the use of mental-health care, leads to substance use. Methods: Data came from the 5-wave, longitudinal Fragile Families and Child Wellbeing (FFCW) Study, an investigation of a cohort of nearly 5,000 births, which oversampled non-marital births. FFCW examined newborns biological mothers and fathers, all of whom lived in the United States. The adults were initially interviewed between 1998 and 2000 (the period of the cohort's births); they were then re-interviewed for four times over 10 years. FFCW measured mental health-related variables, level of drug use, and social structural and demographic factors, all of which are also measured by the present study. Respondents in our study's two final subsamples had responded to every FFCW interview item we would use in constructing our final model's variables. Our subsample of mothers totaled 3,477 women, from whom 5,987 person-waves were derived. Our subsample of fathers totaled 2,096 men, yielding 3,543 person-waves. Results: We used STATA generalized estimating equations for panel data, and found some evidence to support the self-medication hypothesis. In addition, our results indicated that the relationship of substance use to the use of mental-health care was gender-specific. Conclusions/Importance: Empirical evidence from this study only partially supported the self-medication hypothesis; the co-occurrence of depression and substance abuse in our sample was also reflective of social structural and demographic variables and of prior substance use variables.",
keywords = "self-medication hypothesis, substance use, temporal-ordered model",
author = "Lo, {Celia C.} and Cheng, {Tyrone C.} and {De La Rosa}, {Iv{\'a}n A.}",
year = "2015",
month = "8",
day = "24",
doi = "10.3109/10826084.2014.998236",
language = "English",
volume = "50",
pages = "1274--1283",
journal = "Substance Use and Misuse",
issn = "1082-6084",
publisher = "Informa Healthcare",
number = "10",

}

Depression and Substance Use : A Temporal-Ordered Model. / Lo, Celia C.; Cheng, Tyrone C.; De La Rosa, Iván A.

In: Substance Use and Misuse, Vol. 50, No. 10, 24.08.2015, p. 1274-1283.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Depression and Substance Use

T2 - A Temporal-Ordered Model

AU - Lo, Celia C.

AU - Cheng, Tyrone C.

AU - De La Rosa, Iván A.

PY - 2015/8/24

Y1 - 2015/8/24

N2 - Background and Objectives: This study sought empirical evidence for the self-medication hypothesis. It asked whether diagnosis of depression, together with the use of mental-health care, leads to substance use. Methods: Data came from the 5-wave, longitudinal Fragile Families and Child Wellbeing (FFCW) Study, an investigation of a cohort of nearly 5,000 births, which oversampled non-marital births. FFCW examined newborns biological mothers and fathers, all of whom lived in the United States. The adults were initially interviewed between 1998 and 2000 (the period of the cohort's births); they were then re-interviewed for four times over 10 years. FFCW measured mental health-related variables, level of drug use, and social structural and demographic factors, all of which are also measured by the present study. Respondents in our study's two final subsamples had responded to every FFCW interview item we would use in constructing our final model's variables. Our subsample of mothers totaled 3,477 women, from whom 5,987 person-waves were derived. Our subsample of fathers totaled 2,096 men, yielding 3,543 person-waves. Results: We used STATA generalized estimating equations for panel data, and found some evidence to support the self-medication hypothesis. In addition, our results indicated that the relationship of substance use to the use of mental-health care was gender-specific. Conclusions/Importance: Empirical evidence from this study only partially supported the self-medication hypothesis; the co-occurrence of depression and substance abuse in our sample was also reflective of social structural and demographic variables and of prior substance use variables.

AB - Background and Objectives: This study sought empirical evidence for the self-medication hypothesis. It asked whether diagnosis of depression, together with the use of mental-health care, leads to substance use. Methods: Data came from the 5-wave, longitudinal Fragile Families and Child Wellbeing (FFCW) Study, an investigation of a cohort of nearly 5,000 births, which oversampled non-marital births. FFCW examined newborns biological mothers and fathers, all of whom lived in the United States. The adults were initially interviewed between 1998 and 2000 (the period of the cohort's births); they were then re-interviewed for four times over 10 years. FFCW measured mental health-related variables, level of drug use, and social structural and demographic factors, all of which are also measured by the present study. Respondents in our study's two final subsamples had responded to every FFCW interview item we would use in constructing our final model's variables. Our subsample of mothers totaled 3,477 women, from whom 5,987 person-waves were derived. Our subsample of fathers totaled 2,096 men, yielding 3,543 person-waves. Results: We used STATA generalized estimating equations for panel data, and found some evidence to support the self-medication hypothesis. In addition, our results indicated that the relationship of substance use to the use of mental-health care was gender-specific. Conclusions/Importance: Empirical evidence from this study only partially supported the self-medication hypothesis; the co-occurrence of depression and substance abuse in our sample was also reflective of social structural and demographic variables and of prior substance use variables.

KW - self-medication hypothesis

KW - substance use

KW - temporal-ordered model

UR - http://www.scopus.com/inward/record.url?scp=84945471044&partnerID=8YFLogxK

U2 - 10.3109/10826084.2014.998236

DO - 10.3109/10826084.2014.998236

M3 - Article

C2 - 25594110

AN - SCOPUS:84945471044

VL - 50

SP - 1274

EP - 1283

JO - Substance Use and Misuse

JF - Substance Use and Misuse

SN - 1082-6084

IS - 10

ER -