Discovery of CGS 27023A, a nonpeptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits

D. P. Rotella, E. K. Bayburt, M. P. Capparelli, B. J. Carroll, R. Goldstein, M. R. Justice, L. Zhu, S. Hu, R. A. Melton, L. Freyer, R. L. Golding, J. R. Doughty, S. Spirito, V. Bloncuzzi, D. Wilson, E. M. Byrne, V. Ganu, D. T. Parker

Research output: Contribution to journalComment/debate

Original languageEnglish
Pages (from-to)301-305
Number of pages5
JournalChemtracts
Volume11
Issue number4
StatePublished - 1 Apr 1998

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Rotella, D. P., Bayburt, E. K., Capparelli, M. P., Carroll, B. J., Goldstein, R., Justice, M. R., Zhu, L., Hu, S., Melton, R. A., Freyer, L., Golding, R. L., Doughty, J. R., Spirito, S., Bloncuzzi, V., Wilson, D., Byrne, E. M., Ganu, V., & Parker, D. T. (1998). Discovery of CGS 27023A, a nonpeptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits. Chemtracts, 11(4), 301-305.