Discovery of CGS 27023A, a nonpeptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits

D. P. Rotella, E. K. Bayburt, M. P. Capparelli, B. J. Carroll, R. Goldstein, M. R. Justice, L. Zhu, S. Hu, R. A. Melton, L. Freyer, R. L. Golding, J. R. Doughty, S. Spirito, V. Bloncuzzi, D. Wilson, E. M. Byrne, V. Ganu, D. T. Parker

Research output: Contribution to journalComment/debate

Original languageEnglish
Pages (from-to)301-305
Number of pages5
JournalChemtracts
Volume11
Issue number4
StatePublished - 1 Apr 1998

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Matrix Metalloproteinase Inhibitors
Cartilage
Rabbits
CGS 27023A

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Rotella, D. P., Bayburt, E. K., Capparelli, M. P., Carroll, B. J., Goldstein, R., Justice, M. R., ... Parker, D. T. (1998). Discovery of CGS 27023A, a nonpeptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits. Chemtracts, 11(4), 301-305.
Rotella, D. P. ; Bayburt, E. K. ; Capparelli, M. P. ; Carroll, B. J. ; Goldstein, R. ; Justice, M. R. ; Zhu, L. ; Hu, S. ; Melton, R. A. ; Freyer, L. ; Golding, R. L. ; Doughty, J. R. ; Spirito, S. ; Bloncuzzi, V. ; Wilson, D. ; Byrne, E. M. ; Ganu, V. ; Parker, D. T. / Discovery of CGS 27023A, a nonpeptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits. In: Chemtracts. 1998 ; Vol. 11, No. 4. pp. 301-305.
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title = "Discovery of CGS 27023A, a nonpeptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits",
author = "Rotella, {D. P.} and Bayburt, {E. K.} and Capparelli, {M. P.} and Carroll, {B. J.} and R. Goldstein and Justice, {M. R.} and L. Zhu and S. Hu and Melton, {R. A.} and L. Freyer and Golding, {R. L.} and Doughty, {J. R.} and S. Spirito and V. Bloncuzzi and D. Wilson and Byrne, {E. M.} and V. Ganu and Parker, {D. T.}",
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Rotella, DP, Bayburt, EK, Capparelli, MP, Carroll, BJ, Goldstein, R, Justice, MR, Zhu, L, Hu, S, Melton, RA, Freyer, L, Golding, RL, Doughty, JR, Spirito, S, Bloncuzzi, V, Wilson, D, Byrne, EM, Ganu, V & Parker, DT 1998, 'Discovery of CGS 27023A, a nonpeptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits', Chemtracts, vol. 11, no. 4, pp. 301-305.

Discovery of CGS 27023A, a nonpeptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits. / Rotella, D. P.; Bayburt, E. K.; Capparelli, M. P.; Carroll, B. J.; Goldstein, R.; Justice, M. R.; Zhu, L.; Hu, S.; Melton, R. A.; Freyer, L.; Golding, R. L.; Doughty, J. R.; Spirito, S.; Bloncuzzi, V.; Wilson, D.; Byrne, E. M.; Ganu, V.; Parker, D. T.

In: Chemtracts, Vol. 11, No. 4, 01.04.1998, p. 301-305.

Research output: Contribution to journalComment/debate

TY - JOUR

T1 - Discovery of CGS 27023A, a nonpeptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits

AU - Rotella, D. P.

AU - Bayburt, E. K.

AU - Capparelli, M. P.

AU - Carroll, B. J.

AU - Goldstein, R.

AU - Justice, M. R.

AU - Zhu, L.

AU - Hu, S.

AU - Melton, R. A.

AU - Freyer, L.

AU - Golding, R. L.

AU - Doughty, J. R.

AU - Spirito, S.

AU - Bloncuzzi, V.

AU - Wilson, D.

AU - Byrne, E. M.

AU - Ganu, V.

AU - Parker, D. T.

PY - 1998/4/1

Y1 - 1998/4/1

UR - http://www.scopus.com/inward/record.url?scp=0031754071&partnerID=8YFLogxK

M3 - Comment/debate

AN - SCOPUS:0031754071

VL - 11

SP - 301

EP - 305

JO - Chemtracts

JF - Chemtracts

SN - 1431-9268

IS - 4

ER -