Discovery of CGS 27023A, a nonpeptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits

D. P. Rotella, E. K. Bayburt, M. P. Capparelli, B. J. Carroll, R. Goldstein, M. R. Justice, L. Zhu, S. Hu, R. A. Melton, L. Freyer, R. L. Golding, J. R. Doughty, S. Spirito, V. Bloncuzzi, D. Wilson, E. M. Byrne, V. Ganu, D. T. Parker

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