Efficient soluble polymer-supported tartrate/Ti catalyst for asymmetric oxidation of prochiral sulfides

Jinshan Gao, Hongchao Guo, Shangzhong Liu, Min Wang

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Abstract

A group of soluble polymer-supported chiral tartrate ligands was prepared by liquid-phase synthesis with ligand diversity strategy. Moderate to excellent chemical yields and enantiomeric excesses were obtained by using soluble polymer-supported tartrate ester in asymmetric oxidation of prochiral sulfides using Ti(O-i-Pr)4/cumyl hydroperoxide, and the workup was greatly simplified. The influence of substituent in chiral tartrate ligands on the enantioselectivities of the reaction was disclosed.

Original languageEnglish
Pages (from-to)8453-8455
Number of pages3
JournalTetrahedron Letters
Volume48
Issue number48
DOIs
StatePublished - 26 Nov 2007

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Sulfides
Polymers
Ligands
Oxidation
Catalysts
Enantioselectivity
Esters
Liquids
tartaric acid

Cite this

Gao, Jinshan ; Guo, Hongchao ; Liu, Shangzhong ; Wang, Min. / Efficient soluble polymer-supported tartrate/Ti catalyst for asymmetric oxidation of prochiral sulfides. In: Tetrahedron Letters. 2007 ; Vol. 48, No. 48. pp. 8453-8455.
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Efficient soluble polymer-supported tartrate/Ti catalyst for asymmetric oxidation of prochiral sulfides. / Gao, Jinshan; Guo, Hongchao; Liu, Shangzhong; Wang, Min.

In: Tetrahedron Letters, Vol. 48, No. 48, 26.11.2007, p. 8453-8455.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Liu, Shangzhong

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N2 - A group of soluble polymer-supported chiral tartrate ligands was prepared by liquid-phase synthesis with ligand diversity strategy. Moderate to excellent chemical yields and enantiomeric excesses were obtained by using soluble polymer-supported tartrate ester in asymmetric oxidation of prochiral sulfides using Ti(O-i-Pr)4/cumyl hydroperoxide, and the workup was greatly simplified. The influence of substituent in chiral tartrate ligands on the enantioselectivities of the reaction was disclosed.

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