Evidence for the synchronous replication of mitochondrial DNA during the yeast cell cycle

Stephen F. Cottrell, Lee H. Lee

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The nature of mitochondrial DNA replication during the synchronous cell cycle in the yeast, Saccharomyces cerevisiae has been investigated by examining the rate of labeled DNA precursor incorporation into specific segments of the mitochondrial genome at defined points during synchronous growth. The movement of label uptake from one area of the DNA to another at different times during the synchronous cell cycle indicates mitochondrial DNA replication to be a synchronous process during this time with most or all molecules at the same point in replication at any given time during the cell cycle.

Original languageEnglish
Pages (from-to)1350-1356
Number of pages7
JournalBiochemical and Biophysical Research Communications
Issue number4
Publication statusPublished - 31 Aug 1981


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