Previous research has focused on how happiness is independently associated with political orientation and religiosity. The current study instead explored how political orientation and religiosity interact in establishing levels of happiness. Data from both the 2012 General Social Survey and the 2005 World Values Survey were used. Results from both data sets support prior research by showing a positive association between happiness and both political conservatism and religiosity. Importantly, it was found that political conservatism and religiosity interact in predicting happiness levels. Specifically, the current results suggest that religiosity has a greater effect on happiness for more politically conservative individuals compared to more politically liberal individuals.