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Imidazopyrimidines, potent inhibitors of p38 MAP kinase
Kenneth C. Rupert
, James R. Henry
, John H. Dodd
, Scott A. Wadsworth
, Druie E. Cavender
, Gilbert C. Olini
, Bohumila Fahmy
,
John J. Siekierka
Chemistry and Biochemistry
Research output
:
Contribution to journal
›
Article
›
peer-review
293
Scopus citations
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Keyphrases
Potent Inhibitor
100%
P38 MAP Kinase
100%
Imidazopyrimidine
100%
Mitogen-activated Protein Kinase
50%
Inflammatory Cytokines
50%
Interleukin-1β
50%
Crohn's Disease
50%
Inflammatory Conditions
50%
Rheumatologic Diseases
50%
Cytokine Release
50%
Pharmacology, Toxicology and Pharmaceutical Science
Mitogen Activated Protein Kinase P38
100%
Cytokine
100%
Tumor Necrosis Factor
100%
Inflammation
50%
Rheumatoid Arthritis
50%
Crohn's Disease
50%
Inflammatory Arthritis
50%
Immunology and Microbiology
Tumor Necrosis Factor
100%
Proinflammatory Cytokine
50%
Interleukin-1
50%
Inflammatory Arthritis
50%
Crohn's Disease
50%
Cytokine Release
50%
Biochemistry, Genetics and Molecular Biology
Tumor Necrosis Factor
100%
P38 Mitogen-Activated Protein Kinases
100%
Interleukin-1
50%
Cytokine Release
50%
Proinflammatory Cytokine
50%