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Kinetic mechanism of indole-3-glycerol phosphate synthase
Sandra Schlee
, Susanne Dietrich
, Tomasz Kurćon
, Pamela Delaney
,
Nina M. Goodey
, Reinhard Sterner
Chemistry and Biochemistry
Research output
:
Contribution to journal
›
Article
›
peer-review
18
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Scopus citations
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Dive into the research topics of 'Kinetic mechanism of indole-3-glycerol phosphate synthase'. Together they form a unique fingerprint.
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Keyphrases
Substrate Binding
100%
Phosphate
100%
Active Loop
100%
Indole
100%
Kinetic Mechanism
100%
β-glycerophosphate
100%
Indole-3-glycerol Phosphate Synthase
100%
Conformational Motions
75%
Kinetic Model
50%
Step Kinetics
50%
Tryptophan
25%
Monitoring Change
25%
Active Sites
25%
Mutagenesis
25%
Kinetic Data
25%
Reaction Dynamics
25%
Fluorophore
25%
Binding Mechanism
25%
Chemical Transformation
25%
Reaction Mechanism
25%
Conformational Change
25%
Conformational Transition
25%
Molecular Dynamics Simulation
25%
Steady-state Kinetics
25%
Sulfolobus Solfataricus
25%
Rate-limiting Step
25%
Data Monitoring
25%
Four-step
25%
Fluorescent Dye
25%
Global Fitting
25%
Tryptophan Metabolism
25%
Chemical Mechanism
25%
Multi-level Transformation
25%
N-terminal Extension
25%
Crystal Structure Analysis
25%
Enzyme Conversion
25%
Phosphate Conversion
25%
Dye Fluorescence
25%
Product Release
25%
Overall Reaction
25%
Flexible Loop
25%
Kinetic Measurements
25%
Structure Motion
25%
Induced Fit
25%
Biochemistry, Genetics and Molecular Biology
Synthase
100%
Glycerol
100%
Active Site
57%
Enzyme
42%
Motion
42%
Conformational Change
28%
Tryptophan
28%
Wild Type
14%
Steady State
14%
N-Terminus
14%
Structure Analysis
14%
Crystal Structure
14%
Mutagenesis
14%
Anabolism
14%
Sulfolobus solfataricus
14%
Flexible Loop
14%