Markov processes in single molecule fluorescence

Research output: Contribution to journalReview articlepeer-review

35 Scopus citations


This article examines the current status of Markov processes in single molecule fluorescence. For molecular dynamics to be described by a Markov process, the Markov process must include all states involved in the dynamics and the first-passage time (FPT) distributions out of those states must be describable by a simple exponential law. The observation of non-exponential FPT distributions or other evidence of non-Markovian dynamics is common in single molecule studies and offers an opportunity to expand the Markov model to include new dynamics or states that improve understanding of the system.

Original languageEnglish
Pages (from-to)285-296
Number of pages12
JournalCurrent Opinion in Colloid and Interface Science
Issue number6
StatePublished - Dec 2007


  • Hidden Markov models
  • Markov process
  • Molecular memory
  • Reaction rate theory
  • Single molecule fluorescence


Dive into the research topics of 'Markov processes in single molecule fluorescence'. Together they form a unique fingerprint.

Cite this