TY - JOUR
T1 - Mathematical modelling and control of echinococcus in Qinghai Province, China
AU - Wu, Liumei
AU - Song, Baojun
AU - Du, Wen
AU - Lou, Jie
PY - 2013/4
Y1 - 2013/4
N2 - In this paper, two mathematical models, the baseline model and the intervention model, are proposed to study the transmission dynamics of echinococcus. A global forward bifurcation completely characterizes the dynamical behavior of the baseline model. That is, when the basic reproductive number is less than one, the disease-free equilibrium is asymptotically globally stable; when the number is greater than one, the endemic equilibrium is asymptotically globally stable. For the intervention model, however, the basic reproduction number alone is not enough to describe the dynamics, particularly for the case where the basic reproductive number is less then one. The emergence of a backward bifurcation enriches the dynamical behavior of the model. Applying these mathematical models to Qinghai Province, China, we found that the infection of echinococcus is in an endemic state. Furthermore, the model appears to be supportive of human interventions in order to change the landscape of echinococcus infection in this region.
AB - In this paper, two mathematical models, the baseline model and the intervention model, are proposed to study the transmission dynamics of echinococcus. A global forward bifurcation completely characterizes the dynamical behavior of the baseline model. That is, when the basic reproductive number is less than one, the disease-free equilibrium is asymptotically globally stable; when the number is greater than one, the endemic equilibrium is asymptotically globally stable. For the intervention model, however, the basic reproduction number alone is not enough to describe the dynamics, particularly for the case where the basic reproductive number is less then one. The emergence of a backward bifurcation enriches the dynamical behavior of the model. Applying these mathematical models to Qinghai Province, China, we found that the infection of echinococcus is in an endemic state. Furthermore, the model appears to be supportive of human interventions in order to change the landscape of echinococcus infection in this region.
KW - Backward bifurcation
KW - Echinococcosis
KW - Global stability
KW - Mathematical model
UR - http://www.scopus.com/inward/record.url?scp=84874857006&partnerID=8YFLogxK
U2 - 10.3934/mbe.2013.10.425
DO - 10.3934/mbe.2013.10.425
M3 - Article
C2 - 23458307
AN - SCOPUS:84874857006
SN - 1547-1063
VL - 10
SP - 425
EP - 444
JO - Mathematical Biosciences and Engineering
JF - Mathematical Biosciences and Engineering
IS - 2
ER -