Mono- and Di-2,2,2-trichloroethyl Acetals as Protecting Groups

John L. Isidor, Robert M. Carlson

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

Mono- and di-2,2,2-trichloroethyl acetals have been selectively prepared in good yields by acid-catalyzed alcohol exchange with 2,2,2-trichloroethanol and dimethyl or diethyl acetals. A nonacidic and aprotic reductive cleavage using activated zinc dust in ethyl acetate or THE regenerates the carbonyl.

Original languageEnglish
Pages (from-to)554-556
Number of pages3
JournalJournal of Organic Chemistry
Volume38
Issue number3
DOIs
StatePublished - 1 Feb 1973

Fingerprint Dive into the research topics of 'Mono- and Di-2,2,2-trichloroethyl Acetals as Protecting Groups'. Together they form a unique fingerprint.

  • Cite this