Opiate withdrawal: The result of conditioning or physiological mechanisms?

Debra Zellner, Robert J. Dacanay, Anthony L. Riley

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Although it has been suggested that opiate withdrawal responses might be conditioned compensatory responses elicited by drug-associated stimuli, the present results do not support such a view. Withdrawal, as measured by an aversion to a saccharin solution following the termination of morphine administration, occured independent of the presence of morphine-paired environmental or temporal cues. These results suggest that withdrawal is most likely the result of some physiological mechanism, rather than the result of conditioning.

Original languageEnglish
Pages (from-to)175-180
Number of pages6
JournalPharmacology, Biochemistry and Behavior
Volume20
Issue number2
DOIs
StatePublished - 1 Jan 1984

Fingerprint

Opiate Alkaloids
Morphine
Saccharin
Cues
Pharmaceutical Preparations
Conditioning (Psychology)

Keywords

  • Aversions
  • Compensatory classical conditioning
  • Withdrawal

Cite this

Zellner, Debra ; Dacanay, Robert J. ; Riley, Anthony L. / Opiate withdrawal : The result of conditioning or physiological mechanisms?. In: Pharmacology, Biochemistry and Behavior. 1984 ; Vol. 20, No. 2. pp. 175-180.
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Opiate withdrawal : The result of conditioning or physiological mechanisms? / Zellner, Debra; Dacanay, Robert J.; Riley, Anthony L.

In: Pharmacology, Biochemistry and Behavior, Vol. 20, No. 2, 01.01.1984, p. 175-180.

Research output: Contribution to journalArticle

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