Prediction of residues involved in inhibitor specificity in the dihydrofolate reductase family

Keyphrases

• Inhibitor Specificity 100%
• Methylenetetrahydrofolate Reductase (MTHFR) 100%
• Strong Correlation 40%
• Active Sites 40%
• Correlation Analysis 40%
• Similarity Measure 20%
• Sequence Homology 20%
• Ligand Discrimination 20%
• Adenosine 20%
• Parasitic Infection 20%
• Multiple Sequence Alignment 20%
• Current Prediction 20%
• Amino Acid Sequence 20%
• Amino Acid Composition 20%
• Specificity Determinants 20%
• FG Loop 20%
• Protein Family 20%
• Ligand-binding Domain 20%
• Similarity Score 20%
• Opportunistic Infections 20%
• Binding Residues 20%
• Human Homolog 20%
• Pathogenic Organisms 20%

Biochemistry, Genetics and Molecular Biology

• Dihydrofolate Reductase 100%
• Active Site 75%
• Binding Domain 25%
• Amino Acid Composition 25%
• Peptide Sequence 25%
• Sequence Alignment 25%
• Sequence Homology 25%
• Protein Family 25%
• Adenosine 25%