Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNAI

Patricia A. Reichel, William C. Merrick, John Siekierka, Michael B. Mathews

Research output: Contribution to journalArticleResearchpeer-review

78 Citations (Scopus)

Abstract

A small RNA accumulating late in adenovirus infection is required for efficient protein synthesis, although not specifically for the translation of viral proteins. This RNA maintains the activity of an initiation factor catalysing the earliest step of polypeptide chain initiation.

Original languageEnglish
Pages (from-to)196-200
Number of pages5
JournalNature
Volume313
Issue number5999
DOIs
StatePublished - 1 Dec 1985

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Peptide Initiation Factors
Adenoviridae
RNA
Viruses
Adenoviridae Infections
Viral Proteins
Proteins
Peptides

Cite this

Reichel, Patricia A. ; Merrick, William C. ; Siekierka, John ; Mathews, Michael B. / Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNAI. In: Nature. 1985 ; Vol. 313, No. 5999. pp. 196-200.
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Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNAI. / Reichel, Patricia A.; Merrick, William C.; Siekierka, John; Mathews, Michael B.

In: Nature, Vol. 313, No. 5999, 01.12.1985, p. 196-200.

Research output: Contribution to journalArticleResearchpeer-review

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