Silver Effect in Regiodivergent Gold-Catalyzed Hydroaminations

Marcos Veguillas, Georgina M. Rosair, Magnus W.P. Bebbington, Ai Lan Lee

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

We report a silver-induced switching of regioselectivity in gold-catalyzed reactions, and we provide mechanistic evidence to suggest a true "silver effect": that is, one that is implicated in the catalytic process itself, via σ-gold π-silver acetylides. These results are of significance because they clearly show that the use of silver as halide abstractors in gold-catalyzed reactions may result in "silver effects" when terminal alkyne substrates are involved.

Original languageEnglish
Pages (from-to)2552-2557
Number of pages6
JournalACS Catalysis
Volume9
Issue number3
DOIs
StatePublished - 1 Mar 2019

Keywords

  • digold
  • gold
  • gold acetylide
  • hydroamination
  • regiodivergent
  • silver
  • silver-effect

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