Studies on a total synthesis of the microbial immunosuppresive agent FR901483

Chemistry

• Lactam 100%
• Enolates 66%
• Natural Product 66%
• Ketone 33%
• Stereoselectivity 33%
• Cyclic Structure 33%
• Nonane 33%
• Ring Formation 33%
• Oxaziridine 33%
• Epimer 33%
• Cyclohexanedione 33%
• Ketal 33%
• Immunosuppressive Agent 33%
• Alkylation 33%
• hydroxylation 33%
• Carbamate 33%
• Chloride 33%
• Amine 33%

Keyphrases

• Azabicyclo[3.3.1]nonane 33%
• Annulation 33%
• Protection of Alcohols 33%