Synthesis and P-388 Antitumor Properties of the Four Diastereomeric l-Hydroxy-3,4-diaminocyclohexane-Cl₂Pt^II Complexes

Keyphrases

• 1,2-Diaminocyclohexane 100%
• Antitumor Properties 100%
• Bis-carbamate 100%
• Positive Control 50%
• Cisplatin 50%
• Stereochemistry 50%
• Diamine 50%
• Diols 50%
• Alcohol 50%
• Hydroboration-oxidation 50%
• Antileukemic Activity 50%
• Activity in Vivo 50%
• Epoxy 50%
• Murine Leukemia 50%
• X-ray Crystallographic Analysis 50%
• Leukemia Model 50%
• Relative Stereochemistry 50%

Chemistry

• Diastereomer 100%
• Stereochemistry 100%
• Antitumor 100%
• Carbamates 100%
• Cisplatin 50%
• Diol 50%
• X-Ray Crystallographic Analysis 50%
• Hydroboration Oxidation 50%
• Antileucemic 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Leukemia P 388 100%
• Cisplatin 50%
• Ethanol 50%
• Carbamic Acid 50%
• Carbamic Acid Derivative 50%
• Murine Leukemia 50%