The Critical Role of Organic Chemistry in Drug Discovery

Research output: Contribution to journalShort surveypeer-review

14 Scopus citations


Small molecules remain the backbone for modern drug discovery. They are conceived and synthesized by medicinal chemists, many of whom were originally trained as organic chemists. Support from government and industry to provide training and personnel for continued development of this critical skill set has been declining for many years. This Viewpoint highlights the value of organic chemistry and organic medicinal chemists in the complex journey of drug discovery as a reminder that basic science support must be restored.

Original languageEnglish
Pages (from-to)1315-1316
Number of pages2
JournalACS Chemical Neuroscience
Issue number10
StatePublished - 19 Oct 2016


  • AZT
  • drug discovery
  • organic chemistry
  • small molecules


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