The relationships between leptin and measures of fitness and fatness are dependent upon obesity status in youth

Peter A. Hosick, Robert G. McMurray, Dan M. Cooper

Research output: Contribution to journalArticle

8 Scopus citations


The relationship between peak aerobic fitness (peakVO2) and plasma leptin was assessed in 25 normal (BMI < 85th %tile) and 25 overweight (BMI > 85th %tile) youth, ages 7-17 years. In the overall analysis peakVO2 was related to leptin when expressed in mL/kg/min (R 2 =.516, p <.0001), or as ml/kgFFM/min (R2 =.127, p =.01). The relationships between peakVO2 and leptin were no longer significant when percent bodyfat was added to the models. In subanalyses by weight groups, peakVO2: leptin relationships were not evident for normal weight, but remained for overweight youth. In conclusion the relationship between aerobic fitness and leptin in youth is dependent upon weight status.

Original languageEnglish
Pages (from-to)195-204
Number of pages10
JournalPediatric Exercise Science
Issue number2
Publication statusPublished - May 2010


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