The synthesis of (2S)-4,4-difluoroglutamyl γ-peptides based on Garner's aldehyde and fluoro-reformatsky chemistry

Keyphrases

• Hydrolases 100%
• Fluoro 100%
• Reformatsky 100%
• Peptide-based 100%
• Garner's Aldehyde 100%
• Compound II 50%
• Fluorophore 50%
• General Utility 50%
• Mechanistic Probes 50%
• Organofluorine 50%
• Reformatsky Reaction 50%
• Non-fluorinated 50%
• Ethyl Bromoacetate 50%
• Optically Active 50%
• Difluoroamino 50%
• Fluorinated Analogs 50%
• Fluorinated 50%
• Isopeptide 50%
• Current Goal 50%

Chemistry

• Chemistry 100%
• Aldehyde 100%
• Fluorine 50%
• Reformatsky Reaction 50%
• Ethyl 50%
• Serine 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Hydrolase 100%
• Aldehyde 100%
• Serine 50%