Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K

D. P. Rotella; D. S. Yamashita; H. J. Oh; I. N. Uzinskas; K. F. Erhard; A. C. Allen; R. C. Haltiwanger; B. Zhao; W. W. Smith; S. S. Abdel-Meguid; K. D. Alessio; C. A. Jansen; M. S. McQueney; T. A. Tomoszek; M. A. Levy; D. F. Veber

Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K

D. P. Rotella, D. S. Yamashita, H. J. Oh, I. N. Uzinskas, K. F. Erhard, A. C. Allen, R. C. Haltiwanger, B. Zhao, W. W. Smith, S. S. Abdel-Meguid, K. D. Alessio, C. A. Jansen, M. S. McQueney, T. A. Tomoszek, M. A. Levy, D. F. Veber

Chemistry and Biochemistry

Research output: Contribution to journal › Comment/debate

Original language	English
Pages (from-to)	272-275
Number of pages	4
Journal	Chemtracts
Volume	12
Issue number	4
State	Published - Apr 1999

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Rotella, D. P., Yamashita, D. S., Oh, H. J., Uzinskas, I. N., Erhard, K. F., Allen, A. C., Haltiwanger, R. C., Zhao, B., Smith, W. W., Abdel-Meguid, S. S., Alessio, K. D., Jansen, C. A., McQueney, M. S., Tomoszek, T. A., Levy, M. A., & Veber, D. F. (1999). Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K. Chemtracts, 12(4), 272-275.

@article{bc0e9963cd42426d9a5f7f46ce09b5b2,

title = "Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K",

author = "Rotella, {D. P.} and Yamashita, {D. S.} and Oh, {H. J.} and Uzinskas, {I. N.} and Erhard, {K. F.} and Allen, {A. C.} and Haltiwanger, {R. C.} and B. Zhao and Smith, {W. W.} and Abdel-Meguid, {S. S.} and Alessio, {K. D.} and Jansen, {C. A.} and McQueney, {M. S.} and Tomoszek, {T. A.} and Levy, {M. A.} and Veber, {D. F.}",

year = "1999",

month = apr,

language = "English",

volume = "12",

pages = "272--275",

journal = "Chemtracts",

issn = "1431-9268",

publisher = "Data Trace Publishing Co.",

number = "4",

}

Rotella, DP, Yamashita, DS, Oh, HJ, Uzinskas, IN, Erhard, KF, Allen, AC, Haltiwanger, RC, Zhao, B, Smith, WW, Abdel-Meguid, SS, Alessio, KD, Jansen, CA, McQueney, MS, Tomoszek, TA, Levy, MA & Veber, DF 1999, 'Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K', Chemtracts, vol. 12, no. 4, pp. 272-275.

TY - JOUR

T1 - Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K

AU - Rotella, D. P.

AU - Yamashita, D. S.

AU - Oh, H. J.

AU - Uzinskas, I. N.

AU - Erhard, K. F.

AU - Allen, A. C.

AU - Haltiwanger, R. C.

AU - Zhao, B.

AU - Smith, W. W.

AU - Abdel-Meguid, S. S.

AU - Alessio, K. D.

AU - Jansen, C. A.

AU - McQueney, M. S.

AU - Tomoszek, T. A.

AU - Levy, M. A.

AU - Veber, D. F.

PY - 1999/4

Y1 - 1999/4

UR - http://www.scopus.com/inward/record.url?scp=0032827833&partnerID=8YFLogxK

M3 - Comment/debate

AN - SCOPUS:0032827833

SN - 1431-9268

VL - 12

SP - 272

EP - 275

JO - Chemtracts

JF - Chemtracts

IS - 4

ER -

Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K

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