Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K

D. P. Rotella; D. S. Yamashita; H. J. Oh; I. N. Uzinskas; K. F. Erhard; A. C. Allen; R. C. Haltiwanger; B. Zhao; W. W. Smith; S. S. Abdel-Meguid; K. D. Alessio; C. A. Jansen; M. S. McQueney; T. A. Tomoszek; M. A. Levy; D. F. Veber

Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K

D. P. Rotella
, D. S. Yamashita
, H. J. Oh
, I. N. Uzinskas
, K. F. Erhard
, A. C. Allen
, R. C. Haltiwanger
, B. Zhao
, W. W. Smith
, S. S. Abdel-Meguid
, K. D. Alessio
, C. A. Jansen
, M. S. McQueney
, T. A. Tomoszek
, M. A. Levy
, D. F. Veber

Chemistry and Biochemistry

Research output: Contribution to journal › Comment/debate

Original language	English
Pages (from-to)	272-275
Number of pages	4
Journal	Chemtracts
Volume	12
Issue number	4
State	Published - Apr 1999

Cite this

Rotella, D. P., Yamashita, D. S., Oh, H. J., Uzinskas, I. N., Erhard, K. F., Allen, A. C., Haltiwanger, R. C., Zhao, B., Smith, W. W., Abdel-Meguid, S. S., Alessio, K. D., Jansen, C. A., McQueney, M. S., Tomoszek, T. A., Levy, M. A., & Veber, D. F. (1999). Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K. Chemtracts, 12(4), 272-275.

@article{bc0e9963cd42426d9a5f7f46ce09b5b2,

title = "Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K",

author = "Rotella, \{D. P.\} and Yamashita, \{D. S.\} and Oh, \{H. J.\} and Uzinskas, \{I. N.\} and Erhard, \{K. F.\} and Allen, \{A. C.\} and Haltiwanger, \{R. C.\} and B. Zhao and Smith, \{W. W.\} and Abdel-Meguid, \{S. S.\} and Alessio, \{K. D.\} and Jansen, \{C. A.\} and McQueney, \{M. S.\} and Tomoszek, \{T. A.\} and Levy, \{M. A.\} and Veber, \{D. F.\}",

year = "1999",

month = apr,

language = "English",

volume = "12",

pages = "272--275",

journal = "Chemtracts",

issn = "1431-9268",

publisher = "Data Trace Publishing Co.",

number = "4",

}

Rotella, DP, Yamashita, DS, Oh, HJ, Uzinskas, IN, Erhard, KF, Allen, AC, Haltiwanger, RC, Zhao, B, Smith, WW, Abdel-Meguid, SS, Alessio, KD, Jansen, CA, McQueney, MS, Tomoszek, TA, Levy, MA & Veber, DF 1999, 'Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K', Chemtracts, vol. 12, no. 4, pp. 272-275.

TY - JOUR

T1 - Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K

AU - Rotella, D. P.

AU - Yamashita, D. S.

AU - Oh, H. J.

AU - Uzinskas, I. N.

AU - Erhard, K. F.

AU - Allen, A. C.

AU - Haltiwanger, R. C.

AU - Zhao, B.

AU - Smith, W. W.

AU - Abdel-Meguid, S. S.

AU - Alessio, K. D.

AU - Jansen, C. A.

AU - McQueney, M. S.

AU - Tomoszek, T. A.

AU - Levy, M. A.

AU - Veber, D. F.

PY - 1999/4

Y1 - 1999/4

UR - https://www.scopus.com/pages/publications/0032827833

M3 - Comment/debate

AN - SCOPUS:0032827833

SN - 1431-9268

VL - 12

SP - 272

EP - 275

JO - Chemtracts

JF - Chemtracts

IS - 4

ER -

Use of x-ray co-crystal structures and molecular modeling to design potent and selective nonpeptide inhibitors of cathepsin K

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