Vortioxetine differentially modulates MK-801-induced changes in visual signal detection task performance and locomotor activity

Keyphrases

• Attention Function 16%
• Attention Impairment 8%
• Brain Exposure 8%
• Brain Regions 8%
• Cognitive Dysfunction 8%
• Cognitive Function 8%
• Determining Functionals 8%
• Functional Status 8%
• Glutamate Neurotransmission 8%
• Hyperlocomotion 16%
• Kinetic Interaction 8%
• Locomotion 8%
• Locomotor Activity 100%
• Major Depressive Disorder 25%
• MK-801 100%
• Multimodal Antidepressants 8%
• N-methyl-D-aspartate Receptor Antagonist 8%
• Neurotransmission 8%
• Non-competitive 8%
• Non-inferiority Trial 8%
• Patient Demographics 8%
• Pharmacodynamics 8%
• Plasma Exposure 8%
• Scopolamine 8%
• Signal Detection Task 100%
• Task Performance 100%
• Theoretical Mechanism 8%
• Visual Signals 100%
• Vortioxetine 100%

Neuroscience

• Antidepressant 8%
• Blood Plasma 8%
• Cognitive Disorders 8%
• Cognitive Function 8%
• Dizocilpine-Induced Hyperactivity 8%
• Glutamic Acid 8%
• Locomotion 8%
• Locomotor Activity 100%
• Major Depressive Disorder 25%
• NMDA Receptor Antagonist 8%
• Scopolamine 8%
• Synaptic Transmission 16%
• Vortioxetine 100%

Pharmacology, Toxicology and Pharmaceutical Science

• Antidepressant 8%
• Clinical Research 8%
• Cognitive Defect 8%
• Dizocilpine-Induced Hyperactivity 8%
• Functional Status 8%
• Glutamic Acid 8%
• Major Depression 25%
• NMDA Receptor Antagonist 8%
• Pharmacodynamics 8%
• Scopolamine 8%
• Vortioxetine 100%