Web-based interventions for youth internalizing problems: A systematic review

Jazmin A. Reyes-Portillo, Laura Mufson, Laurence L. Greenhill, Madelyn S. Gould, Prudence W. Fisher, Naomi Tarlow, Moira A. Rynn

Research output: Contribution to journalReview articlepeer-review

74 Scopus citations


Results Of the 14,001 citations initially identified, 25 articles met inclusion criteria for Web-based interventions. These described 9 programs, of which 8 were Internet based and 1 was a mobile application. No Web-based interventions for suicide prevention were identified. Of the randomized controlled trials (n = 14) and open trials (n = 3) identified, 10 reported significant postintervention reductions in symptoms of depression and/or anxiety or improvements in diagnostic ratings, with small to large effect sizes. Many of these studies also reported significant improvements at follow-up. The methodological quality of the studies varied. Many programs were limited by their small sample sizes and use of waitlist or no-treatment control groups.

Conclusion There is limited evidence for the effectiveness of Web-based interventions for youth depression and anxiety. Additional research and program development are needed to fill the current gaps in the literature.

Objective To review published reports on Web-based treatment and prevention programs for depression, anxiety, and suicide prevention in children, adolescents, and emerging adults.

Method A systematic search of the PsycINFO, PubMed, Medline, and Web of Science databases was conducted in December 2013. Programs were classified according to evidence-base level (Well-Established, Probably Efficacious, Possibly Efficacious, Experimental, and Of Questionable Efficacy).

Original languageEnglish
Pages (from-to)1254-1270.e5
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Issue number12
StatePublished - 1 Dec 2014


  • Web-based intervention
  • anxiety
  • depression
  • emerging adult


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